Science 2.0

Reimagining How Science Works

From attention signals to evidence signals. From prestige to truth. Here's what science could look like with the right infrastructure.

"Science today: Humans propose, humans experiment, humans review, journals gatekeep, citations rank."

"Science 2.0: AI proposes from evidence gaps, automated labs execute, continuous open review, evidence grades rank, knowledge updates in real-time."

The Problem Today

Current System Rewards

  • Citations — popularity, not validity
  • Journal prestige — brand, not rigor
  • Novelty — interesting, not replicated
  • Positive results — 95% of negatives never published

What Actually Matters

  • Methodology quality — how was it done?
  • Replication status — does it hold up?
  • Statistical power — could it detect the effect?
  • Conflicts of interest — who benefits?

Science runs on attention signals. The next infrastructure layer must rank claims by evidence strength — replications, contradictions, methodology — not popularity.

Follow The Money

The $2.9T Research Machine

Where the money flows — and the signal breaks

Global R&D ($2.9T)

🇨🇳China
🇺🇸USA
🇪🇺EU+UK
🇯🇵Japan
🌍Rest

Institutions

Corporations71%
Universities13%
Gov Labs12%
Nonprofits3%

~3M Papers/Year

40% cited60% never cited
The Problem

Citations measure attention, not evidence. 60% of papers are invisible. ~50% don't replicate.

But where does money actually go?

The Institutional Tax

$506B burned before research starts

Gov Labs12% overhead
Corporations15% overhead
Nonprofits25% overhead
Universities34% overhead

Of "research" money:

Personnel 80%
20%

For a $1M university grant:

$340K

overhead

$528K

salaries

$132K

science

~13%reaches the bench

The 11 Phases of Science

Science has distinct phases from question to practice. Each can be reimagined with the right infrastructure. Click any phase to explore how it transforms.

💡
Phase 1

Question

Intuition, fundabilityAI hypothesis market from evidence gaps

Socratic maintains live map of ALL claims, evidence strength, gaps, contradictions. AI generates testable hypotheses: "If A and B, then C should follow — but C untested."

Hypothesis generation engineExpected value calculatorPublic hypothesis marketplace
🔒
Phase 2

Pre-Reg

Optional, gameableBlockchain + prediction markets

Hypothesis submitted to blockchain — timestamped, immutable, encrypted until complete. Prediction market: others bet on P(true), creating prior from crowd wisdom.

Blockchain/immutable layerPrediction marketsDeviation tracking
💰
Phase 3

Funding

Prestige-based, 85% wasteEvidence-based + Researcher FICO

Score = Evidence quality (30%) + Novelty (25%) + Researcher FICO (20%) + Feasibility (15%) + Impact (10%). No human review for initial filter.

Researcher FICO systemFunding optimizerAgency integrations
📐
Phase 4

Design

Manual, underpoweredAI-optimized, simulated

AI generates optimal sample size, controls, randomization, blinding. Pre-analysis plan auto-generated. 10,000 simulations run before real experiment.

Design optimizerPower simulationsPre-analysis generator
📊
Phase 5

Data

Manual, manipulableAutomated labs, blockchain

Robotic data collection, direct instrument → database, no human touch. Every data point timestamped on blockchain, cannot be modified.

Lab integrationsImmutable data layerAnomaly detection
🔬
Phase 6

Analysis

Cherry-picked, p-hackedPre-registered auto-execution

Pre-registered analysis runs automatically: data locked → script runs → results committed. Multiverse analysis shows ALL reasonable variants.

Auto-executionMultiverse engineReplication simulator
👁️
Phase 7

Review

6-18 months, unpaidContinuous, AI + paid experts

Immediate deposit. AI Review (instant): GRIM, p-curve, methods. Expert Review: top 5 auto-invited, paid $500-2000, named, citable.

AI pre-reviewReviewer FICOReview bounties
📰
Phase 8

Publication

Journal gatekeepersImmediate deposit, curation

No journals, no gatekeepers. All work immediately public. "Journals" become curators. Ranked by evidence grade, not journal name.

Mandatory depositCuration layerNegative result valorization
🔄
Phase 9

Replication

Rare, unfunded (40%)Bounty economy (>90%)

Replication value = Impact × Uncertainty × Feasibility. Funders post bounties, labs compete, paid regardless of outcome.

Value calculatorBounty marketplaceLab matching
🔗
Phase 10

Integration

Siloed, manual SLRsReal-time knowledge graph

Every claim auto-extracted, normalized, linked. SUPPORTS / CONTRADICTS / EXTENDS mapped. Real-time updates when new papers publish.

Real-time graphDownstream propagationNL querying
🏥
Phase 11

Translation

17 years to practice<1 year, EHR-integrated

Evidence threshold triggers: Grade A → alert clinicians. AI drafts guidelines, humans review. Days, not years.

EHR integrationClinical decision supportFeedback loop

The 5-Layer Infrastructure Stack

Science 2.0 requires five interconnected infrastructure layers. Socratic is Layer 1 — the evidence foundation everything else builds on.

5

Translation

Clinical decision supportEHR integrationsGuideline generatorReal-world feedback
4

Incentives

Prediction marketsReplication bountiesReview paymentsResearcher FICO
3

Execution

Lab automationAuto-analysis pipelinesPre-registration infraImmutable data
2

Intelligence

AI ScientistDesign optimizerAI peer reviewReplication calculator
1

Evidence

← Socratic Today
Claim extractionEvidence gradingContradiction mappingPaper analysis

What Would Change

Idea to Publication

2-5 years2-5 months

Faster iteration, less bureaucracy

Replication Rate

~40%>90%

Pre-registration + incentives

Discovery to Practice

17 years<1 year

Real-time evidence translation

Funding Waste

~85%<30%

Evidence-based allocation

Retraction Detection

YearsDays

Automated integrity checks

Negative Results Published

~5%100%

Mandatory registration

The goal: Transform science from a prestige economy to a truth economy.

Roadmap

Building Science 2.0 is a multi-year journey. Here's how we get there.

Phase 1: Evidence Foundation

Now → 6 months

Complete claim extraction, grading, and relationship mapping

Phase 2: Intelligence Layer

6-18 months

AI Scientist, SLR generator, AI pre-review

Phase 3: Execution Layer

18-36 months

Pre-registration integration, data repository, lab partnerships

Phase 4: Incentives Layer

36-60 months

Prediction markets, replication bounties, Researcher FICO

Phase 5: Translation Layer

60+ months

EHR integration, clinical decision support, feedback loops

This is what we're building toward.

Socratic is the foundation — the evidence layer that makes everything else possible. Every claim extracted, every contradiction mapped, every evidence grade assigned brings us closer.