ArticleThe Journal of clinical endocrinology and metabolism2002
Insulin resistance, intra-abdominal fat, cardiovascular risk factors, and androgens in healthy young women with type 1 diabetes mellitus.
Article in The Journal of clinical endocrinology and metabolism, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02045290 (Metformin Therapy for Overweight Adolescents With Type 1 Diabetes), which is not on this map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Metformin Therapy for Overweight Adolescents With Type 1 Diabetes (T1D)--Insulin Clamp Ancillary Study for Assessment of Insulin Resistance
Who cites it
9 citing papers in PubMed.
- Plasma adiponectin concentration in relation to severity of coronary atherosclerosis and cardiovascular risk factors in middle-aged men.Endocrine · 2004Trial
- Metabolic control and body mass index in patients with type 1 diabetes on different insulin regimens.Bosnian journal of basic medical sciences · 2004Trial
- Insulin Resistance in Type 1 Diabetes: Pathophysiological, Clinical, and Therapeutic Relevance.Endocrine reviews · 2025Review
- The Effects of Resistance Exercise Training on Skeletal Muscle Metabolism and Insulin Resistance Development in Female Rodents with Type 1 Diabetes.Journal of diabetes research · 2024Article
- Sodium-glucose cotransporter 2 inhibitors in type 1 diabetes: a missed opportunity for cardiovascular protection?The Medical journal of Australia · 2022Article
- Protective effects of physical activity against health risks associated with type 1 diabetes: "Health benefits outweigh the risks".World journal of diabetes · 2022Review
- Clinically meaningful and lasting HbADiabetologia · 2018Article
- Lipoprotein subfraction cholesterol distribution is proatherogenic in women with type 1 diabetes and insulin resistance.Diabetes · 2010Article
- Insulin resistance in adolescents with type 1 diabetes and its relationship to cardiovascular function.The Journal of clinical endocrinology and metabolism · 2010 · on this mapArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The increased cardiovascular risk in type 1 diabetes may be related, at least in part, to insulin resistance. The aim of this study was to assess the relationships between insulin sensitivity, abdominal fat, androgens, lipids, and blood pressure in 10 premenopausal women with type 1 diabetes (mean +/- SD, hemoglobin A1c 8.1 +/- 1.0%) and 10 nondiabetic body mass index-matched controls. Insulin sensitivity (glucose infusion rate during euglycemic-hyperinsulinemic clamp) was significantly less in the type 1 diabetes group than in controls (49.3 +/- 14.8 vs. 73.2 +/- 21.6 micromol/min x kg fat free mass, respectively, P = 0.01). The two groups were similar with respect to lipids, androgens, energy expenditure, physical activity, blood pressure, and abdominal adiposity (intra-abdominal fat by four-slice computed tomography and central abdominal fat by dual-energy x-ray absorptiometry). There were no relationships between glucose infusion rate, abdominal adiposity, and androgen levels in subjects with type 1 diabetes, in contrast to controls. Our results demonstrate greater insulin resistance in a group of premenopausal women with type 1 diabetes compared with nondiabetic controls, unrelated to abdominal adiposity, lipids, or androgens.
Indexed as
Identifiers
11889158What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.