ArticleProceedings of the National Academy of Sciences of the United States of America2002
Ancient mitochondrial haplotypes and evidence for intragenic recombination in a gynodioecious plant.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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42 citing papers in PubMed, 133 citations in OpenAlex.
- The Impact of Pleistocene Glacial Cycles on the Evolutionary Diversification of the Arctic-Alpine Silene acaulis Species Complex.Molecular ecology · 2026Article
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- Mitochondrial polymorphism of sea beet (Beta vulgaris ssp. maritima), a species with cytoplasmic male sterility.PloS one · 2025Article
- Long-read transcriptome and other genomic resources for the angiosperm Silene noctiflora.G3 (Bethesda, Md.) · 2021Article
- Variation in plastid genomes in the gynodioecious species Silene vulgaris.BMC plant biology · 2019Article
- Do angiosperms with highly divergent mitochondrial genomes have altered mitochondrial function?Mitochondrion · 2019Article
- Recombination and intraspecific polymorphism for the presence and absence of entire chromosomes in mitochondrial genomes.Heredity · 2019Article
- Population Genetics of Paramecium Mitochondrial Genomes: Recombination, Mutation Spectrum, and Efficacy of Selection.Genome biology and evolution · 2019Article
- Article
- Old Trade, New Tricks: Insights into the Spontaneous Mutation Process from the Partnering of Classical Mutation Accumulation Experiments with High-Throughput Genomic Approaches.Genome biology and evolution · 2019Review
- Homologous recombination changes the context of Cytochrome b transcription in the mitochondrial genome of Silene vulgaris KRA.BMC genomics · 2018Article
- Evidence for intragenic recombination and selective sweep in an effector gene ofEvolutionary applications · 2018Article
- Patterns of Genome-Wide Nucleotide Diversity in the Gynodioecious Plant Thymus vulgaris Are Compatible with Recent Sweeps of Cytoplasmic Genes.Genome biology and evolution · 2018Article
- Non-coding RNA may be associated with cytoplasmic male sterility in Silene vulgaris.Journal of experimental botany · 2017Article
- Article
- Can paternal leakage maintain sexually antagonistic polymorphism in the cytoplasm?Journal of evolutionary biology · 2015Article
- Mitochondrial atp9 genes from petaloid male-sterile and male-fertile carrots differ in their status of heteroplasmy, recombination involvement, post-transcriptional processing as well as accumulation of RNA and protein product.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2014Article
- On the importance of balancing selection in plants.The New phytologist · 2014Review
- Article
- Biparental inheritance of organelles in Pelargonium: evidence for intergenomic recombination of mitochondrial DNA.Planta · 2013Article
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2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Because of their extremely low nucleotide mutation rates, plant mitochondrial genes are generally not expected to show variation within species. Remarkably, we found nine distinct cytochrome b sequence haplotypes in the gynodioecious alpine plant Silene acaulis, with two or more haplotypes coexisting locally in each of three sampled regions. Moreover, there is evidence for intragenic recombination in the history of the haplotype sample, implying at least transient heteroplasmy of mitochondrial DNA (mtDNA). Heteroplasmy might be achieved by one of two potential mechanisms, either continuous coexistence of subgenomic fragments in low stoichiometry, or occasional paternal leakage of mtDNA. On the basis of levels of synonymous nucleotide substitutions, the average divergence time between haplotypes is estimated to be at least 15 million years. Ancient coalescence of extant haplotypes is further indicated by the paucity of fixed differences in haplotypes obtained from related species, a pattern expected under trans-specific evolution. Our data are consistent with models of frequency-dependent selection on linked cytoplasmic male-sterility factors, the putative molecular basis of females in gynodioecious populations. However, associations between marker loci and the inferred male-sterility genes can be maintained only with very low rates of recombination. Heteroplasmy and recombination between divergent haplotypes imply unexplored consequences for the evolutionary dynamics of gynodioecy, a widespread plant breeding system.
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