ReviewJAMA2002
New evidence for stroke prevention: scientific review.
Review in JAMA, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 3 syntheses or guidelines pooled it, 297 citations in OpenAlex.
- Multiple sclerosis and stroke: a systematic review and meta-analysis.BMC neurology · 2019Pooled it
- Effects of vitamin E on stroke subtypes: meta-analysis of randomised controlled trials.BMJ (Clinical research ed.) · 2010Pooled it
- [European Stroke Organisation 2008 guidelines for managing acute cerebral infarction or transient ischemic attack : part 2].Der Nervenarzt · 2008Guideline
- The effects of curcumin-piperine supplementation on inflammatory, oxidative stress and metabolic indices in patients with ischemic stroke in the rehabilitation phase: a randomized controlled trial.Nutrition journal · 2023Trial
- Adequacy of control of cardiovascular risk factors in ambulatory patients with type 2 diabetes attending diabetes out-patients clinic at a county hospital, Kenya.BMC endocrine disorders · 2017Trial
- Case management for blood pressure and lipid level control after minor stroke: PREVENTION randomized controlled trial.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2014Trial
- Study protocol of the YOU CALL--WE CALL TRIAL: impact of a multimodal support intervention after a "mild" stroke.BMC neurology · 2010Trial
- Epidemiology and future trend predictions of ischemic stroke based on the global burden of disease study 1990-2021.Communications medicine · 2025Article
- Understanding the mechanism of acupuncture in acute cerebral infraction through a proteomic analysis: protocol for a prospective randomized controlled trial.Frontiers in neuroscience · 2024Article
- Association of multiple sclerosis with stroke: A comprehensive review.Health science reports · 2024Article
- Associations Between Potentially Modifiable and Nonmodifiable Risk Factors and Gait Speed in Middle- and Older-Aged Adults: Results From the Canadian Longitudinal Study on Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021Article
- Multimorbidity in Finnish and Swedish speaking Finns; association with daily habits and socioeconomic status - Nordic EpiLung cross-sectional study.Preventive medicine reports · 2021Article
- Modeling Survival in Patients With Brain Stroke in the Presence of Competing Risks.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2021Article
- Patient- and Physician-Level Factors Associated With Adherence to C-CHANGE Recommendations in Primary Care Settings in Ontario.CJC open · 2020Article
- Article
- Access to health care for older people with intellectual disability: a modelling study to explore the cost-effectiveness of health checks.BMC public health · 2019Article
- Identifying treatment related problems and associated factors among hospitalized post-stroke patients through medication management review: A multi-center study.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2019Article
- Acute effects of air pollution on ischaemic stroke onset and deaths: a time-series study in Changzhou, China.BMJ open · 2018Article
- Atopic diseases/diathesis and subsequent ischemic stroke among patients with bipolar disorder: A nationwide longitudinal study.PloS one · 2018Article
- Observational
6 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextStroke is a major cause of morbidity and mortality, and the application of evidence for stroke prevention varies considerably.
objectiveTo review the most recent, high-quality evidence for primary and secondary stroke prevention. DATA SOURCES AND STUDY SELECTION: Searches of MEDLINE, The Cochrane Library, and the ACP Journal Club were performed to identify English-language articles published from 1998 to 2001 that focused on primary and secondary stroke prevention. The references of each retrieved article were scanned, and experts in the field were contacted to identify additional relevant articles. DATA EXTRACTION: Each of the articles was appraised, and its quality was graded with levels of evidence based on specific scientific methods that affect a study's validity. DATA SYNTHESIS: For primary prevention of stroke, adequate blood pressure reduction, and treatment of hyperlipidemia, use of antithrombotic therapy in patients with atrial fibrillation and of antiplatelet therapy in patients with myocardial infarction are effective and supported by evidence from several randomized trials. Effective strategies for the secondary prevention of stroke include treatment of hypertension and hyperlipidemia, antithrombotic therapy for patients with atrial fibrillation, antiplatelet therapy, and carotid endarterectomy in patients with severe carotid artery stenosis.
conclusionsStroke is a major public health concern, and a significant body of evidence supports many primary and secondary prevention strategies.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.