ArticleMedicine and science in sports and exercise2003
Time course of improved flow-mediated dilation after short-term exercise training.
Article in Medicine and science in sports and exercise, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Metformin on Insulin Sensitivity and Pan-Arterial Vascular Function in Adults With Metabolic Syndrome
The Effects of Exercise Training on Tumor Vascularity and Response to Neoadjuvant Therapy in Operable Breast Cancer: A Phase I-II Study
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Resting blood pressure reductions following handgrip exercise training and the impact of age and sex: a systematic review and narrative synthesis.Systematic reviews · 2018Pooled it
- PRIME-HF: Novel Exercise for Older Patients with Heart Failure. A Pilot Randomized Controlled Study.Journal of the American Geriatrics Society · 2020Trial
- Trial
- PRIME: A Novel Low-Mass, High-Repetition Approach to Improve Function in Older Adults.Medicine and science in sports and exercise · 2018Trial
- Forearm Skin Blood Flow After Kinesiology Taping in Healthy Soccer Players: An Exploratory Investigation.Journal of athletic training · 2015Trial
- The effect of exercise intensity on endothelial function in physically inactive lean and obese adults.PloS one · 2014Trial
- Unlocking the barriers to improved functional capacity in the elderly: rationale and design for the "Fit for Life trial".Contemporary clinical trials · 2013Trial
- Impact of chronic intermittent external compressions on forearm blood flow capacity in humans.European journal of applied physiology · 2011Trial
- Rapid vascular modifications to localized rhythmic handgrip training and detraining: vascular conditioning and deconditioning.European journal of applied physiology · 2010Trial
- Effects of short-term endurance exercise training on vascular function in young males.European journal of applied physiology · 2009Trial
- Preserved contribution of nitric oxide to baseline vascular tone in deconditioned human skeletal muscle.The Journal of physiology · 2005Trial
- Impact of a Novel Training Approach on Hemodynamic and Vascular Profiles in Older Adults.Journal of aging and physical activity · 2022Article
- Strength training with blood flow restriction - a novel therapeutic approach for older adults with sarcopenia? A case report.Clinical interventions in aging · 2019Review
- Similar pattern of change in V̇oAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2017Article
- Short-term exercise training improves flow-mediated dilation and circulating angiogenic cell number in older sedentary adults.Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2016Article
- Isometric exercise training lowers resting blood pressure and improves local brachial artery flow-mediated dilation equally in men and women.European journal of applied physiology · 2016Article
- Maximal intermittent handgrip strategy: design and evaluation of an exercise protocol and a grip tool.Clinical interventions in aging · 2016Article
- Effects of disturbed blood flow during exercise on endothelial function: a time course analysis.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2016Article
- Dysregulated metabolism contributes to oncogenesis.Seminars in cancer biology · 2015Review
- Therapeutic properties of aerobic training after a cancer diagnosis: more than a one-trick pony?Journal of the National Cancer Institute · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose was to determine the influence of a unilateral localized short-term handgrip training protocol on brachial artery flow-mediated dilation (BAFMD) and to examine the time course of such changes.
methodsFourteen healthy males (age: 26 +/- 5.7 yr) underwent high-resolution ultrasonographic brachial artery assessments before (V1), during (V2-V7), and at the end of 4 wk (V8) of 60% maximal voluntary contraction handgrip training (20 min.d-1, 5 d.wk-1) of the nondominant arm.
resultsBefore training resting diameters were similar between the trained (nondominant) and untrained (dominant) arms. A 2 (trained and untrained arms) x 2 (V1 and V8) repeated measure ANOVA revealed a significant main (P = 0.02 and P = 0.03) and interaction effect (P = 0.05 and P = 0.01) for the percent and absolute change in BAFMD. BAFMD improved 62% and 70%, respectively from V1 to V8, for the percent and absolute change. Subsequent linear orthogonal polynomial contrasts indicate both the percent and absolute change in BAFMD were statistically different at V2 (end of week 1 and 4 training days) from V1. These unilateral changes were not accompanied by changes in resting artery diameter, hemodynamic measures, hematological markers, and indices of heart rate variability suggesting the change may be locally mediated.
conclusionsThis study shows a localized short-term exercise-training program resulted in significant improvements in BAFMD in the trained arm compared with the untrained arm and suggests this occurred after only 4 d of training.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.