Evidence mapPaperPMID 14350806Full record

ArticleArchives of biochemistry and biophysics1955

Influence of nicotinic acid on serum cholesterol in man.

R ALTSCHUL, A HOFFER, J D STEPHEN

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Archives of biochemistry and biophysics, 1955. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01384058 (The Effect of Ezetimibe 10 mg, Simvastatin 20 mg and the Combination of Simvastatin 20 mg Plus 10 mg Ezetimibe on Low Density Lipoprotein), which is not on this map. Cited by 140 papers.

0numbers the graph read from it
0cells of the map it votes in
140citing papers in PubMed
39.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01384058 phase4completedstarted 2007, after this paper: background citation

The Effect of Ezetimibe 10 mg, Simvastatin 20 mg and the Combination of Simvastatin 20 mg Plus 10 mg Ezetimibe on Low Density Lipoprotein (LDL)-Subfractions in Patients With Type 2 Diabetes

Ran2007Enrolled41Registered outcomes5Posted comparisons0ConditionsDiabetes Mellitus Type 2, HypercholesterolemiaArmsEzetimibe, Ezetimibe 10/Simvastatin 20, simvastatin
Open the trial in the graph
3 · Its place in the literature

Who cites it

140 citing papers in PubMed, 722 citations in OpenAlex.

  1. A Detoxification Intervention for Gulf War Illness: A Pilot Randomized Controlled Trial.International journal of environmental research and public health · 2019
    Trial
  2. Trial
  3. Trial
  4. Trial
  5. Coronary drug project: experience with niacin. Coronary Drug Project Research Group.European journal of clinical pharmacology · 1991 · on this map
    Trial
  6. Trial
  7. Trial
  8. Hypolipaemic drugs and coronary heart disease.Journal of clinical pathology. Supplement (Royal College of Pathologists) · 1975
    Trial
  9. Review
  10. Lipoprotein(a): structural basis, bidirectional risk, and therapeutic frontiers.Journal of clinical biochemistry and nutrition · 2026
    Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Disulfiram-Mitigating Unintended Effects.Antibiotics (Basel, Switzerland) · 2023
    Review
  19. Review
  20. Article

80 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

R ALTSCHUL
A HOFFER
J D STEPHEN
Regina General Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BloodNicotinic AcidsCholesterolHumansMaleNiacinCholesterolNiacinNicotinic AcidsBLOODCHOLESTEROL/in bloodNICOTINIC ACID/effects

Identifiers

PMID14350806
OpenAlexW2078578691

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.