Evidence map›Paper›PMID 15010605›Full record

ArticlePlant molecular biology2003

Cestrum yellow leaf curling virus (CmYLCV) promoter: a new strong constitutive promoter for heterologous gene expression in a wide variety of crops.

Livia Stavolone, Maria Kononova, Sandra Pauli, Antonio Ragozzino, Peter de Haan, Steve Milligan, Kay Lawton, Thomas Hohn

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Plant molecular biology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. From Structure to Function of Promoters and 5'UTRs in Maize.International journal of molecular sciences · 2026
    Review
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  8. Review
  9. Article
  10. Article
  11. Jan and mini-Jan, a model system for potato functional genomics.bioRxiv : the preprint server for biology · 2024
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Livia StavoloneFriedrich Miescher Institute, Maulbeerstrasse 66, 4058 Basel, Switzerland. l.stavolone@area.ba.cnr.it
Maria Kononova
Sandra Pauli
Antonio Ragozzino
Peter de Haan
Steve Milligan
Kay Lawton
Thomas Hohn
Friedrich Miescher Institute · CHTriangle · USCentro di Ricerca per la Patologia Vegetale · ITFriedrich Miescher Institute · CHJanssen (Netherlands) · NLSyngenta (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Appropriately regulated gene expression requires a suitable promoter. A number of promoters have been isolated and shown to be functional in plants, but only a few of them activate transcription of transgenes at high levels constitutively. We report here the cloning and characterization of a novel, constitutively expressed promoter isolated from Cestrum yellow leaf curling virus (CmYLCV), a double-stranded DNA plant pararetrovirus belonging to the Caulimoviridae family. The CmYLCV promoter is highly active in callus, meristems and vegetative and reproductive tissues in Arabidopsis thaliana, Nicotiana tabacum, Lycopersicon esculentum, Zea mays and Oryza sativa. Furthermore, the level of expression is comparable to, or higher than, that from the CaMV 35S, the 'super-promoter' or the maize ubiquitin 1 promoters, three frequently used promoters in agricultural biotechnology. The heritable, strong and constitutive activity in both monocotyledonous and dicotyledonous plants, combined with the extremely narrow CmYLCV host range, makes the CmYLCV promoter an attractive tool for regulating transgene expression in a wide variety of plant species.

Indexed as

ArabidopsisCaulimovirusCestrumEnzyme-Linked Immunosorbent AssayGene DosageGene ExpressionGlucuronidaseGreen Fluorescent ProteinsHistocytochemistryLuminescent ProteinsMicroscopy, FluorescenceNicotianaOryzaPlants, Genetically ModifiedPlasmidsPromoter Regions, GeneticGlucuronidaseGreen Fluorescent ProteinsLuminescent ProteinsRecombinant Fusion Proteins

Identifiers

PMID15010605
OpenAlexW2011804618

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.