Evidence map›Paper›PMID 15064283›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA

Structured representation of the pharmacodynamics section of the summary of product characteristics for antibiotics: application for automated extraction and visualization of their antimicrobial activity spectra.

Catherine Duclos, Gian Luigi Cartolano, Michael Ghez, Alain Venot

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. An iconic language for the graphical representation of medical concepts.BMC medical informatics and decision making · 2008
    Article
  6. An ontology of bacteria to help physicians to compare antibacterial spectra.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2007
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Catherine DuclosLaboratoire d'informatique médicale et de bioinformatique (LIM&BIO), UFR de Santé, Médecine et Biologie Humaine, Paris 13, Bobigny cedex, France. catherine.duclos@avc.ap-hop-paris.fr.
Gian Luigi Cartolano
Michael Ghez
Alain Venot

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to construct automatically a knowledge base concerning the pharmacodynamic properties of antibiotics and a visualization tool.

designThe authors studied the various guidelines used to write the pharmacodynamics section of the Summary of Product Characteristics (SPC) for antibiotics and constructed a conceptual model of the information. Particular words, syntagms, and punctuation elements were marked in the SPC texts, and automatic extraction was then used to build a knowledge base. This base was used to create dynamic HTML tables displaying the activity spectra of the antibiotics. MEASUREMENTS: The authors analyzed the performances of automatic extraction (recall and precision).

resultsThe conceptual pharmacodynamics model dealt with antibiotics, pathogens, susceptibility tests, and the prevalence of resistance. Automatic extraction had a recall rate of 97.9% and a precision of 96.2%. The tool displaying antibiotic spectra and resistance prevalences used color codes to identify differences in susceptibility.

conclusionThis tool can provide an overview of the prevalence of resistance as expressed in SPC in primary care settings. Its potential impact should be evaluated.

Indexed as

Artificial IntelligencePharmacopoeias as TopicAnti-Bacterial AgentsBacteriaDrug Resistance, BacterialEuropeHumansModels, TheoreticalProgramming LanguagesTerminology as TopicUnited StatesAnti-Bacterial Agents

Identifiers

PMID15064283
PMCPMC436077

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.