Metformin × body weight & composition

TrialFertility and sterility2004

A randomized, 48-week, placebo-controlled trial of intensive lifestyle modification and/or metformin therapy in overweight women with polycystic ovary syndrome: a pilot study.

Kathleen M Hoeger et al.PubMed ↗Publisher ↗

What the trial testedrandomised · 2004

Randomised comparison

Probably lowered body weight & composition

−16.2−60.2 to −4.40

As reported

difference −16.2, 95% CI −60.2 to −4.40

One number in the abstract

the abstract, start to end

the odds ratio for regular ovulation was 16.2 (95% confidence interval

← favours treatmentfavours comparator →
could be chance
Body weight & composition
−16.2−60.2 to −4.40
MetforminBody weight & composition

Metformin × body weight & compositionhelps?mixed

unlikelylikely
0.500.50 without it
← favours treatmentfavours comparator →
this papermore certainless certain
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The trial

Full record →Abstract, authors, funding and every citing paper · PMID 15302293