ArticleSleep & breathing = Schlaf & Atmung2005
The effect of continuous positive airway pressure on glucose control in diabetic patients with severe obstructive sleep apnea.
Article in Sleep & breathing = Schlaf & Atmung, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 3 syntheses or guidelines pooled it, 142 citations in OpenAlex.
- The role of choroidal thickness in diabetic retinopathy and obstructive sleep apnea syndrome.Sleep & breathing = Schlaf & Atmung · 2016Pooled it
- Effects of continuous positive airway pressure therapy on glycaemic control, insulin sensitivity and body mass index in patients with obstructive sleep apnoea and type 2 diabetes: a systematic review and meta-analysis.NPJ primary care respiratory medicine · 2015Pooled it
- Pooled it
- Metabolic assessments of neurostimulation therapy to reduce apnea (MANTRA) trial: rationale and methods.Sleep & breathing = Schlaf & Atmung · 2026Trial
- Trial
- Effects of a lifestyle intervention on REM sleep-related OSA severity in obese individuals with type 2 diabetes.Journal of sleep research · 2017Trial
- Effect of continuous positive airway pressure on blood pressure and metabolic profile in women with sleep apnoea.The European respiratory journal · 2017Trial
- CPAP therapy for patients with sleep apnea and type 2 diabetes mellitus improves control of blood pressure.Sleep & breathing = Schlaf & Atmung · 2017Trial
- CPAP therapy of obstructive sleep apnea in type 2 diabetics improves glycemic control during sleep.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2008Trial
- Efficacy and patient satisfaction with autoadjusting CPAP with variable expiratory pressure vs standard CPAP: a two-night randomized crossover trial.Sleep & breathing = Schlaf & Atmung · 2007Trial
- Continuous positive airway pressure usage before and after issue of an urgent product defect correction notice following a global Philips recall.Internal medicine journal · 2026Article
- International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023Review
- Investigating the Relationship between Obstructive Sleep Apnoea, Inflammation and Cardio-Metabolic Diseases.International journal of molecular sciences · 2023Review
- Rationale and design of the Hyperglycemic Profiles in Obstructive Sleep Apnea (HYPNOS) trial.Contemporary clinical trials · 2021Article
- Transcriptomic Changes of Murine Visceral Fat Exposed to Intermittent Hypoxia at Single Cell Resolution.International journal of molecular sciences · 2020Article
- Relationship Between Intermittent Hypoxia and Type 2 Diabetes in Sleep Apnea Syndrome.International journal of molecular sciences · 2019Review
- STOP-Bang questionnaire screening for obstructive sleep apnea among Chinese patients with type 2 diabetes mellitus.Archives of medical science : AMS · 2018Article
- VAMONOS (Veterans Affairs' Metabolism, Obstructed and Non-Obstructed Sleep) Study: Effects of CPAP Therapy on Glucose Metabolism in Patients with Obstructive Sleep Apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2017Article
- Serum triglyceride levels in relation to high-density lipoprotein cholesterol (TG-HDL) ratios as an efficient tool to estimate the risk of sleep apnea syndrome in non-overweight Japanese men.Environmental health and preventive medicine · 2016Article
- Sleep: important considerations for the prevention of cardiovascular disease.Current opinion in cardiology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obstructive sleep apnea (OSA) is independently associated with glucose intolerance and insulin resistance, and recent studies have shown that continuous positive airway pressure (CPAP) improves insulin sensitivity. The objective of this study was to describe the change in glycosylated hemoglobin (HbA1c) after treatment with CPAP in patients with type 2 diabetes mellitus and OSA. To test this hypothesis, we performed a retrospective analysis of 38 patients seen in the sleep clinic of an urban public teaching hospital. All patients had OSA and type 2 diabetes mellitus, and their diabetic medication regimen had remained unchanged during the period of CPAP therapy. Sixty-one percent were men, body mass index was 42+/-9.5 kg/m(2), and the Apnea-Hypopnea Index was 53+/-36 per hour. HbA1c before therapy with CPAP was 7.8+/-1.4% and decreased to 7.3+/-1.3% after 134+/-119 days of therapy (p<0.001). Treatment with CPAP leads to a clinically significant drop in HbA1c in patients with type 2 diabetes mellitus and severe OSA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.