Evidence map›Paper›PMID 16360788›Full record

ArticleLancet (London, England)2005

Global prevalence of dementia: a Delphi consensus study.

Cleusa P Ferri, Martin Prince, Carol Brayne, Henry Brodaty, Laura Fratiglioni, Mary Ganguli, Kathleen Hall, Kazuo Hasegawa, Hugh Hendrie, Yueqin Huang and 6 more

9 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Lancet (London, England), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 9 registered trials, which are not on this map. Cited by 1,632 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,632citing papers in PubMed, 15 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04841668 completedstarted 2021, after this paper: background citation

Gut-Brain-axis: Targets for Improvement of Cognition in the Elderly

Ran2021Enrolled50Registered outcomes51Posted comparisons0ConditionsType 2 Diabetes MellitusArmsMetformin
PMID 8013758PMID 30397356PMID 16443885PMID 11118008PMID 18220635PMID 12086935PMID 28500216PMID 12930161PMID 16219009PMID 11602624PMID 28768369PMID 18806222other papers from this trial
Open the trial in the graph
NCT00413621 completednot on this mapstarted 2006, after this paper: background citation

MRI of Alzheimer's Disease Imaging Amyloid Plaques in Persons With and Without Memory Problems

TypeobservationalSponsorNational Institute of Neurological Disorders and Stroke (NINDS)Ran2006Enrolled40ConditionsAlzheimer's Disease
NCT02701855 unknown statusnot on this mapstarted 2014, after this paper: background citation

Retina Microvascular Remodeling and Cognitive Function In Hypertension : Eyebrain

TypeobservationalSponsorInstitute of Cardiometabolism and Nutrition, FranceRan2014 to 2017Enrolled160ConditionsHypertension, Mild Cognitive ImpairmentArmsCognitive tests, Blood test, Brain and aorta RMI, Adaptative optics
NCT03593941 completednot on this mapstarted 2018, after this paper: background citation

Ageing Gut Brain Interactions

TypeobservationalSponsorUniversity of AberdeenRan2018 to 2020Enrolled60ConditionsDementia AlzheimersArmsStandard Diet
NCT04047485 unknown statusnot on this mapstarted 2019, after this paper: background citation

Evaluation of the Effect of Cataract Surgery on Cognitive Function in Very Elderly Patients

TypeobservationalSponsorUniversity of Modena and Reggio EmiliaRan2019 to 2020Enrolled100ConditionsDementia, Mild Cognitive Impairment, Cataract Senile, CataractArmsVisual Acuity, CAM (Confusion Assesment Method), CATQUEST 9-SF, OCT, 6CIT
NCT04972643 nacompletednot on this mapstarted 2012, after this paper: background citation

Department of Psychiatry, Taichung Veterans General Hospital

TypeinterventionalSponsorTaichung Veterans General HospitalRan2012 to 2018Enrolled163ConditionsAlzheimer Disease, Dementia DisorderArmsEPA, DHA, Placebo
NCT05119114 unknown statusnot on this mapstarted 2021, after this paper: background citation

Role of Volumetric Magnetic Resonance Imaging in Evaluation of Different Types of Dementia

TypeobservationalSponsorAssiut UniversityRan2021 to 2023Enrolled40ConditionsDementia, Alzheimer DiseaseArmsMagnetic Resonance Imaging (MRI)
NCT05538455 nacompletednot on this mapstarted 2022, after this paper: background citation

ProCare4Life Pilot 3 Clinical Study: Investigating ProCare4Life Impact on Quality of Life of Elderly Subjects With Neurodegenerative Diseases

TypeinterventionalSponsorCasa di Cura Privata del Policlinico SpARan2022 to 2023Enrolled558ConditionsNeurodegenerative Diseases, Parkinson Disease, Alzheimer Disease, Quality of LifeArmsPC4L solutions
NCT06608589 narecruitingnot on this mapstarted 2023, after this paper: background citation

CONSTELLATIONS Living Lab: Development, Implementation and Evaluation of a Patient-oriented Quality Improvement Program Targeting Care Transitions of Older Adults Living with Major Neurocognitive Disorders and Their Caregivers.

TypeinterventionalSponsorLaval UniversityRan2023 to 2026Enrolled700ConditionsAlzheimer Disease, Dementia, Neurocognitive DeclineArmsCoMPAS+ MNCDs Program - Quality improvement program targeting the care transitions of patients living with a major neurocognitive disorder and their caregivers
3 · Its place in the literature

Who cites it

1,632 citing papers in PubMed, 15 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Pooled it
  14. Pooled it
  15. Pooled it
  16. Trial
  17. Trial
  18. Trial
  19. Article
  20. Article

1,572 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Cleusa P FerriSection of Epidemiology, Institute of Psychiatry, King's College, London, UK. c.ferri@iop.kcl.ac.uk
Martin Prince
Carol Brayne
Henry Brodaty
Laura Fratiglioni
Mary Ganguli
Kathleen Hall
Kazuo Hasegawa
Hugh Hendrie
Yueqin Huang
Anthony Jorm
Colin Mathers
Paulo R Menezes
Elizabeth Rimmer
Marcia Scazufca
Alzheimer's Disease International

Funding

INDIANAPOLIS/IBADAN DEMENTIA PROJECTR01AG009956 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI HALL, KATHLEEN S · 1991 to 2010
$14.0M
NIA NIH HHS R01 AG009956Wellcome Trust
6 · The paper itself

Abstract

background100 years after the first description, Alzheimer's disease is one of the most disabling and burdensome health conditions worldwide. We used the Delphi consensus method to determine dementia prevalence for each world region.

methods12 international experts were provided with a systematic review of published studies on dementia and were asked to provide prevalence estimates for every WHO world region, for men and women combined, in 5-year age bands from 60 to 84 years, and for those aged 85 years and older. UN population estimates and projections were used to estimate numbers of people with dementia in 2001, 2020, and 2040. We estimated incidence rates from prevalence, remission, and mortality.

findingsEvidence from well-planned, representative epidemiological surveys is scarce in many regions. We estimate that 24.3 million people have dementia today, with 4.6 million new cases of dementia every year (one new case every 7 seconds). The number of people affected will double every 20 years to 81.1 million by 2040. Most people with dementia live in developing countries (60% in 2001, rising to 71% by 2040). Rates of increase are not uniform; numbers in developed countries are forecast to increase by 100% between 2001 and 2040, but by more than 300% in India, China, and their south Asian and western Pacific neighbours.

interpretationWe believe that the detailed estimates in this paper constitute the best currently available basis for policymaking, planning, and allocation of health and welfare resources.

Indexed as

Delphi TechniqueGlobal HealthAgedAlzheimer DiseaseCost of IllnessFemaleHumansMaleMeta-Analysis as TopicMiddle AgedPrevalence

Identifiers

PMID16360788
PMCPMC2850264

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

and 3 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.