Evidence mapPaperPMID 16609094Full record

ArticleJAMA2006

Glycemic variability: a hemoglobin A1c-independent risk factor for diabetic complications.

Michael Brownlee, Irl B Hirsch

Registry-linked trialAbstract readEditorialComment
PubMed Publisher
In one paragraph

Article in JAMA, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02624908 (Canagliflozin-Mealtime Insulin Rescue), which is not on this map. Cited by 208 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
208citing papers in PubMed, 7 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02624908 phase4unknown statusstarted 2016, after this paper: background citation

Canagliflozin-Mealtime Insulin Rescue

Ran2016Enrolled40Registered outcomes5Posted comparisons0ConditionsDiabetes Mellitus, Type 2ArmsCanagliflozin, Placebo
Open the trial in the graph
3 · Its place in the literature

Who cites it

208 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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148 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Michael Brownlee
Irl B Hirsch

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Blood Glucose Self-MonitoringDiabetes ComplicationsDiabetes MellitusDinoprostGlycated HemoglobinHumansHyperglycemiaOxidative Stress8-epi-prostaglandin F2alphaDinoprostGlycated Hemoglobin

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.