Evidence map›Paper›PMID 16612394›Full record

ReviewKidney international. Supplement2006

Contrast-induced nephropathy: definition, epidemiology, and patients at risk.

R Mehran, E Nikolsky

3 registry-linked trialsOpen access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Kidney international. Supplement, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 312 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
312citing papers in PubMed, 12 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05037695 phase4unknown statusstarted 2021, after this paper: background citation

SGLT-2 Inhibitors in Prevention of Post-procedural Renal and Cardiovascular Complications aFter PCI Among Patients With Diabetes Mellitus and Coronary Artery Disease: a Prospective, Randomized, Pilot Study (SAFE-PCI)

Ran2021Enrolled40Registered outcomes17Posted comparisons0ConditionsAcute Kidney Injury, Coronary Artery Disease, Diabetes Mellitus, Type 2Armsempagliflozin 25 mg
PMID 30990260PMID 30497881PMID 10511612PMID 11565518PMID 17184637PMID 17699010PMID 18287807PMID 19850388PMID 20686453PMID 23895807PMID 24135581PMID 24226524other papers from this trial
Open the trial in the graph
NCT03164681 unknown statusnot on this mapstarted 2017, after this paper: background citation

Red Blood Cell Distribution Width as a Predictor Marker of Contrast Induced Nephropathy in Patients Undergoing Percutaneous Coronary Intervention

TypeobservationalSponsorAssiut UniversityRan2017 to 2018Enrolled126ConditionsContrast-induced Nephropathy
NCT05283512 narecruitingnot on this mapstarted 2022, after this paper: background citation

Intravenous vs. Oral Hydration to Reduce the Risk of Post-Contrast Acute Kidney Injury After Intravenous Contrast-Enhanced Computed Tomography in Patients With Severe Chronic Kidney Disease (ENRICH): A Randomized Controlled Trial

TypeinterventionalSponsorOdense University HospitalRan2022 to 2027Enrolled254ConditionsContrast-induced Nephropathy, Kidney Injury, Kidney Failure, Chronic, Risk ReductionArmsPreventive treatment with IV-hydration, Preventive treatment with oral hydration
3 · Its place in the literature

Who cites it

312 citing papers in PubMed, 12 syntheses or guidelines pooled it, 874 citations in OpenAlex.

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  14. Dynamic Coronary Roadmap versus standard angiography for percutaneous coronary intervention: the randomised, multicentre DCR4Contrast trial.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024
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  17. Comparison of Different Hydration Strategies in Patients with Very Low-Risk Profiles of Contrast-Induced Nephropathy.Medical science monitor : international medical journal of experimental and clinical research · 2021
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252 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

R MehranCardiovascular Research Foundation, New York, New York, USA. rmehran@crf.org
E Nikolsky
Cardiovascular Research Foundation · USColumbia University Irving Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiological procedures utilizing intravascular iodinated contrast media injections are being widely applied for both diagnostic and therapeutic purposes. This has resulted in an increasing incidence of procedure-related contrast-induced nephropathy (CIN). The definition of CIN includes absolute (> or = 0.5 mg/dl) or relative increase (> or = 25%) in serum creatinine at 48-72 h after exposure to a contrast agent compared to baseline serum creatinine values, when alternative explanations for renal impairment have been excluded. Although the risk of renal function impairment associated with radiological procedures is low (0.6-2.3%) in the general population, it may be very high in selected patient subsets (up to 20%), especially in patients with underlying cardiovascular disease. This review provides information on the known risk factors for the development of CIN, and completes with describing user-friendly CIN risk score based on the readily available information.

Indexed as

AgedAge FactorsAnemiaContrast MediaCreatinineDiabetic NephropathiesHumansIncidenceKidney DiseasesOsmolar ConcentrationRisk FactorsContrast MediaCreatinine

Identifiers

PMID16612394
OpenAlexW2065661664

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.