ArticleNucleic acids research2006
Multiple physical forms of excised group II intron RNAs in wheat mitochondria.
Article in Nucleic acids research, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Recurrent Modular Assembly Drives Independent Origins of Group II Introns Encoding LAGLIDADG Homing Endonucleases.Genome biology and evolution · 2026Article
- Plasma Circular RNAs in Breast Cancer: From Biomarker Potential to Functional Significance.Cancer reports (Hoboken, N.J.) · 2025Review
- Categorizing 161 plant (streptophyte) mitochondrial group II introns into 29 families of related paralogues finds only limited links between intron mobility and intron-borne maturases.BMC ecology and evolution · 2023Article
- Emerging landscape of circFNDC3B and its role in human malignancies.Frontiers in oncology · 2023Review
- Biogenesis and Regulatory Roles of Circular RNAs.Annual review of cell and developmental biology · 2022Review
- Molecular characterization of both transesterification reactions of the group II intron circularization pathway.Nucleic acids research · 2021Article
- Mitochondrial Pentatricopeptide Repeat Protein, EMB2794, Plays a Pivotal Role in NADH Dehydrogenase Subunit nad2 mRNA Maturation in Arabidopsis thaliana.Plant & cell physiology · 2020Article
- Mitochondrial Epigenetics: Non-Coding RNAs as a Novel Layer of Complexity.International journal of molecular sciences · 2020Review
- Two Pentatricopeptide Repeat Proteins Are Required for the Splicing ofFrontiers in plant science · 2020Article
- Article
- Bacterial group II introns generate genetic diversity by circularization and trans-splicing from a population of intron-invaded mRNAs.PLoS genetics · 2018Article
- Three new pentatricopeptide repeat proteins facilitate the splicing of mitochondrial transcripts and complex I biogenesis in Arabidopsis.Journal of experimental botany · 2018Article
- MaizeGenetics · 2018Article
- Molecular roles and function of circular RNAs in eukaryotic cells.Cellular and molecular life sciences : CMLS · 2018Review
- Postsplicing-Derived Full-Length Intron Circles in the Protozoan ParasiteFrontiers in cellular and infection microbiology · 2018Article
- The biogenesis and emerging roles of circular RNAs.Nature reviews. Molecular cell biology · 2016Article
- Circularization pathway of a bacterial group II intron.Nucleic acids research · 2016Article
- The RAD52-like protein ODB1 is required for the efficient excision of two mitochondrial introns spliced via first-step hydrolysis.Nucleic acids research · 2015Article
- The Ll.LtrB intron from Lactococcus lactis excises as circles in vivo: insights into the group II intron circularization pathway.RNA (New York, N.Y.) · 2015Article
- RNA circularization strategies in vivo and in vitro.Nucleic acids research · 2015Review
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2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Plant mitochondrial group II introns do not all possess hallmark ribozymic features such as the bulged adenosine involved in lariat formation. To gain insight into their splicing pathways, we have examined the physical form of excised introns in germinating wheat embryos. Using RT-PCR and cRT-PCR, we observed conventional lariats consistent with a two-step transesterification pathway for introns such as nad2 intron 4, but this was not the case for the cox2 intron or nad1 intron 2. For cox2, we detected full-length linear introns, which possess non-encoded 3'terminaladenosines, as well as heterogeneous circular introns, which lack 3' nucleotide stretches. These observations are consistent with hydrolytic splicing followed by polyadenylation as well as an in vivo circularization pathway, respectively. The presence of both linear and circular species in vivo is supported by RNase H analysis. Furthermore, the nad1 intron 2, which lacks a bulged nucleotide at the branchpoint position, comprised a mixed population of precisely full-length molecules and circular ones which also include a short, discrete block of non-encoded nucleotides. The presence of these various linear and circular forms of excised intron molecules in plant mitochondria points to multiple novel group II splicing mechanisms in vivo.
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