ReviewWorld journal of gastroenterology2006
Drug treatment of functional dyspepsia.
Review in World journal of gastroenterology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.
- Acupuncture for functional dyspepsia.The Cochrane database of systematic reviews · 2014Pooled it
- Efficacy of Gastrosis No.1 compound on functional dyspepsia of spleen and stomach deficiency-cold syndrome: a multi-center, double-blind, placebo-controlled clinical trial.Chinese journal of integrative medicine · 2013Trial
- Efficacy of modified LiuJunZi decoction on functional dyspepsia of spleen-deficiency and qi-stagnation syndrome: a randomized controlled trial.BMC complementary and alternative medicine · 2013Trial
- The Effects of Physical Activity on Functional Dyspepsia: A Mendelian Randomization and Randomized Controlled Study.Journal of neurogastroenterology and motility · 2026Article
- Beyond Thirst: Influence of Bicarbonate Mineral Water on Cardiovascular Risk Factors, Gastrointestinal Function, and Liver Health.Food science & nutrition · 2025Review
- Combined UPLC-Q-TOF-MS/MS and Network Pharmacology to Analyze the Potential Mechanism of Jieyu Fuwei Powder for Functional Dyspepsia Treatment.Current topics in medicinal chemistry · 2025Article
- Effects of Saikosaponin D on Apoptosis, Autophagy, and Morphological Structure of Intestinal Cells of Cajal with Functional Dyspepsia.Combinatorial chemistry & high throughput screening · 2024Article
- Exercise is inversely associated with functional dyspepsia among a sample of Chinese male armed police recruits.BMC gastroenterology · 2023Article
- Functional dyspepsia is associated with lower exercise levels: A population-based study.United European gastroenterology journal · 2020Article
- Paeoniflorin Alleviates Abnormalities in Rats with Functional Dyspepsia by Stimulating the Release of Acetylcholine.Drug design, development and therapy · 2020Article
- Sub-acute and acute toxicity of Ferula asafoetida and Silybum marianum formulation and effect of the formulation on delaying gastric emptying.BMC complementary and alternative medicine · 2019Article
- Effects of Bu-Zhong-Yi-Qi-Tang for the treatment of functional dyspepsia: a feasibility study protocol.Integrative medicine research · 2017Article
- Acupuncture for Functional Dyspepsia: What Strength Does It Have? A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Evidence-based complementary and alternative medicine : eCAM · 2016Review
- Herbal Remedies for Functional Dyspepsia and Traditional Iranian Medicine Perspective.Iranian Red Crescent medical journal · 2015Review
- Comparison of the Effects of pH-Dependent Peppermint Oil and Synbiotic Lactol (Bacillus coagulans + Fructooligosaccharides) on Childhood Functional Abdominal Pain: A Randomized Placebo-Controlled Study.Iranian Red Crescent medical journal · 2015Article
- Acupuncture for Functional Dyspepsia: A Single Blinded, Randomized, Controlled Trial.Evidence-based complementary and alternative medicine : eCAM · 2015Article
- Evaluation ofExperimental and therapeutic medicine · 2013Article
- Efficacy of modified ban xia xie xin decoction on functional dyspepsia of cold and heat in complexity syndrome: a randomized controlled trial.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Translation and validation of the Nepean Dyspepsia Index for functional dyspepsia in China.World journal of gastroenterology · 2009Article
- Exploratory Study of Tegaserod for Dyspepsia in Women Receiving PPIs for Heartburn.Archives of drug information · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Symptomatic improvement of patients with functional dyspepsia after drug therapy is often incomplete and obtained in not more than 60% of patients. This is likely because functional dyspepsia is a heterogeneous disease. Although great advance has been achieved with the consensus definitions of the Rome I and II criteria, there are still some aspects about the definition of functional dyspepsia that require clarification. The Rome criteria explicitly recognise that epigastric pain or discomfort must be the predominant complaint in patients labelled as suffering from functional dyspepsia. However, this strict definition can create problems in the daily primary care clinical practice, where the patient with functional dyspepsia presents with multiple symptoms. Before starting drug therapy it is recommended to provide the patient with an explanation of the disease process and reassurance. A thorough physical examination and judicious use of laboratory data and endoscopy are also indicated. In general, the approach to treat patients with functional dyspepsia based on their main symptom is practical and effective. Generally, patients should be treated with acid suppressive therapy using proton-pump inhibitors if the predominant symptoms are epigastric pain or gastroesophageal reflux symptoms. Although the role of Helicobacter pylori (H pylori) in functional dyspepsia continues to be a matter of debate, recent data indicate that there is modest but clear benefit of eradication of H pylori in patients with functional dyspepsia. In addition, H pylori is a gastric carcinogen and if found it should be eliminated. Although there are no specific diets for patients with FD, it may be helpful to guide the patients on healthy exercise and eating habits.
Indexed as
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.