Evidence mapPaperPMID 16787216Full record

ReviewCurrent medicinal chemistry2006

Emerging role of intravascular ultrasound in the assessment of experimental anti-atherosclerotic therapies.

Stephen J Nicholls, Ilke Sipahi

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current medicinal chemistry, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03771053 (Intravascular Ultrasound Evaluation of the Intervention Effect of Simvastatin Combined With Ezetimibe on Coronary Borderline Lesion in Patients With Stable Angina Pectoris and Diabetes Mellitus Compared With Simvastatin Alone), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03771053 naunknown statusstarted 2018, after this paper: background citation

Intravascular Ultrasound Evaluation of the Intervention Effect of Simvastatin Combined With Ezetimibe on Coronary Borderline Lesion in Patients With Stable Angina Pectoris and Diabetes Mellitus Compared With Simvastatin Alone

Ran2018Enrolled240Registered outcomes7Posted comparisons0ConditionsCoronary Heart DiseaseArmsEzetimibe with simvastatin, simvastatin
Open the trial in the graph
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Stephen J NichollsDepartment of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland OH 44195, USA. nichols1@ccf.org
Ilke Sipahi
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intravascular ultrasound (IVUS) imaging within the coronary arteries has emerged as the gold standard for the quantitation of the extent of atherosclerosis plaque. Studies that have utilized IVUS have enhanced our understanding of the in vivo natural history of atherogenesis. As IVUS can be performed within the same coronary artery at different time points it has become an attractive tool for the assessment of the effect of experimental anti-atherosclerotic strategies on plaque burden. This review will review the evolution of IVUS as an imaging modality and highlight its use to assess a number of interventions that are directed at both modification of existing risk factors and novel targets that are thought to play a pivotal role in the pathogenesis of atheroma formation.

Indexed as

AtherosclerosisBlood VesselsHumansUltrasonography

Identifiers

PMID16787216
OpenAlexW2083959978

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.