ArticleWorld journal of gastroenterology2007
Validity and cost comparison of 14carbon urea breath test for diagnosis of H Pylori in dyspeptic patients.
Article in World journal of gastroenterology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 4 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Urea breath test forWorld journal of gastroenterology · 2024Pooled it
- Non-invasive diagnostic tests for Helicobacter pylori infection.The Cochrane database of systematic reviews · 2018Pooled it
- Diagnostic accuracy of theWiener klinische Wochenschrift · 2017Pooled it
- Accuracy of urea breath test in Helicobacter pylori infection: meta-analysis.World journal of gastroenterology · 2015Pooled it
- Current Helicobacter pylori Infection Is Associated with Early Liver Injury: A Cross-Sectional Study in the General Population.The American journal of tropical medicine and hygiene · 2023Article
- Systematic Review and Meta-Analysis on the Sensitivity and Specificity ofDiagnostics (Basel, Switzerland) · 2022Review
- Diagnostic Value ofClinical and experimental gastroenterology · 2021Article
- Helicobacter pylori infection and the prevalence of hypertension in Chinese adults: The Dongfeng-Tongji cohort.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- Low rate of recurrence of Helicobacter pylori infection in spite of high clarithromycin resistance in Pakistan.BMC gastroenterology · 2013Article
- Relationship between vitamin B12, folate and homocysteine levels and H. pylori infection in patients with functional dyspepsia: a cross-section study.BMC research notes · 2012Article
- Diagnostic accuracy of tests for Helicobacter pylori in an Alaska Native population.World journal of gastroenterology · 2011Article
- Clinical Validation of an Office-Based C-UBT (Heliprobe) for H. pylori Diagnosis in Iranian Dyspeptic Patients.Gastroenterology research and practice · 2011Article
- Frequency of iron deficiency anemia (IDA) among patients with Helicobacter pylori infection.Pakistan journal of medical sciencesArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo validate and compare the cost of microdose 14C urea breath test (UBT) with histology and rapid urease test for the diagnosis of H Pylori.
methodsNinety-four consecutive patients with dyspeptic symptoms undergoing gastroscopy were enrolled. Gastric biopsies were taken for histology and rapid urease test. UBT was performed after gastroscopy by microdose 14C urea capsules. Sensitivity, specificity and accuracy of UBT were calculated and compared with histology and rapid urease test. Cost comparison of these tests was also performed.
resultsH pylori was diagnosed by histology and rapid urease test in 66 (70%) and 61 (65%) patients, while 14C UBT detected infection in 63 (67%). Accuracy of UBT was 93% in comparison with histology while its positive and negative predictive values were 97% and 84%, respectively. Comparison of 14C UBT with rapid urease test gives an accuracy of 96%, with positive and negative predictive values of 95% and 97%, respectively. These results were highly reproducible with a Kappa test (P value<0.001). Cost of histology or rapid urease test with gastroscopy was 110 USD or 95 USD respectively while the cost of UBT was 15 USD.
conclusionMicrodose 14C UBT was comparable to histology and rapid urease test. 14C UBT is an economical, self sufficient and suitable test to diagnose active H pylori infection in less developed countries.
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