Evidence map›Paper›PMID 17512778›Full record

ReviewBiochimica et biophysica acta2007

The Sec14-superfamily and the regulatory interface between phospholipid metabolism and membrane trafficking.

Carl J Mousley, Kimberly R Tyeryar, Patrick Vincent-Pope, Vytas A Bankaitis

Open access · greenAbstract readReview
In one paragraph

Review in Biochimica et biophysica acta, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 80 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. A Sec14 domain protein is required for photoautotrophic growth and chloroplast vesicle formation inProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  7. Review
  8. Article
  9. Article
  10. Saccharomyces cerevisiae-like 1 (SEC14L1) is a prognostic factor in breast cancer associated with lymphovascular invasion.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2018
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. The mutational spectrum of the NF1 gene in neurofibromatosis type I patients from UAE.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2014
    Article
  18. Lipid transport in the lactating mammary gland.Journal of mammary gland biology and neoplasia · 2014
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Carl J MousleyDepartment of Cell and Developmental Biology, Lineberger Comprehensive Cancer Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7090, USA. carl_mousley@med.unc.edu
Kimberly R Tyeryar
Patrick Vincent-Pope
Vytas A Bankaitis
University of North Carolina at Chapel Hill · US

Funding

Role of the Phospholipids in Golgi Secretory FunctionR01GM044530 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BANKAITIS, VYTAS A · 1991 to 2019
$5.6M
NIGMS NIH HHS R01 GM044530
6 · The paper itself

Abstract

A central principle of signal transduction is the appropriate control of the process so that relevant signals can be detected with fine spatial and temporal resolution. In the case of lipid-mediated signaling, organization and metabolism of specific lipid mediators is an important aspect of such control. Herein, we review the emerging evidence regarding the roles of Sec14-like phosphatidylinositol transfer proteins (PITPs) in the action of intracellular signaling networks; particularly as these relate to membrane trafficking. Finally, we explore developing ideas regarding how Sec14-like PITPs execute biological function. As Sec14-like proteins define a protein superfamily with diverse lipid (or lipophile) binding capabilities, it is likely these under-investigated proteins will be ultimately demonstrated as a ubiquitously important set of biological regulators whose functions influence a large territory in the signaling landscape of eukaryotic cells.

Indexed as

AnimalsBiological TransportCarrier ProteinsCrystallizationHumansMembrane LipidsMetabolic Networks and PathwaysModels, MolecularPhosphatidylcholinesPhosphatidylinositolsPhospholipidsPhospholipid Transfer ProteinsProtein BindingSaccharomyces cerevisiae ProteinsSignal TransductionCarrier ProteinsMembrane LipidsPhosphatidylcholinesPhosphatidylinositolsPhospholipidsPhospholipid Transfer ProteinsSaccharomyces cerevisiae ProteinsSEC14L1 protein, humanSec14p-like phosphoinositide-binding p45 protein, ratSEC14 protein, S cerevisiae

Identifiers

PMID17512778
PMCPMC2001170
OpenAlexW2062089314

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.