ArticleEthnicity & disease2007
Design of a family study among high-risk Caribbean Hispanics: the Northern Manhattan Family Study.
Article in Ethnicity & disease, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 24 citations in OpenAlex.
- Hypermethylation ofJournal of the American Heart Association · 2025Article
- Targeted sequencing of linkage region in Dominican families implicates PRIMA1 and the SPATA7-PTPN21-ZC3H14-EML5-TTC8 locus in carotid-intima media thickness and atherosclerotic events.Scientific reports · 2019Article
- Sequencing of Linkage Region on Chromosome 12p11 IdentifiesG3 (Bethesda, Md.) · 2018Article
- Sickle Cell Trait and Renal Function in Hispanics in the United States: The Northern Manhattan Study.Ethnicity & disease · 2017Article
- Rare Variants in NOD1 Associated with Carotid Bifurcation Intima-Media Thickness in Dominican Republic Families.PloS one · 2016Article
- Sirtuin/uncoupling protein gene variants and carotid plaque area and morphology.International journal of stroke : official journal of the International Stroke Society · 2015Article
- Sequencing of candidate genes in Dominican families implicates both rare exonic and common non-exonic variants for carotid intima-media thickness at bifurcation.Human genetics · 2015Article
- Relationship between sirtuin and mitochondrial uncoupling protein genes and carotid artery stiffness.Translational research : the journal of laboratory and clinical medicine · 2015Article
- Quantifying and addressing persistent stroke disparities in Hispanics.Annals of neurology · 2013Article
- Association of the sirtuin and mitochondrial uncoupling protein genes with carotid intima-media thickness.Translational research : the journal of laboratory and clinical medicine · 2012Article
- Follow-up association study of linkage regions reveals multiple candidate genes for carotid plaque in Dominicans.Atherosclerosis · 2012Article
- Fine mapping study reveals novel candidate genes for carotid intima-media thickness in Dominican Republican families.Circulation. Cardiovascular genetics · 2012Article
- Heritability Estimation using Regression Models for Correlation.Journal of biometrics & biostatistics · 2011Article
- A follow-up study for left ventricular mass on chromosome 12p11 identifies potential candidate genes.BMC medical genetics · 2011Article
- Genetic loci for blood lipid levels identified by linkage and association analyses in Caribbean Hispanics.Journal of lipid research · 2011Article
- Genome-wide linkage and peak-wide association study of obesity-related quantitative traits in Caribbean Hispanics.Human genetics · 2011Article
- Association of the sirtuin and mitochondrial uncoupling protein genes with carotid plaque.PloS one · 2011Article
- Genomewide linkage and peakwide association analyses of carotid plaque in Caribbean Hispanics.Stroke · 2010Article
- A comprehensive genetic study on left atrium size in Caribbean Hispanics identifies potential candidate genes in 17p10.Circulation. Cardiovascular genetics · 2010Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
Stroke continues to kill disproportionately more Blacks and Hispanics than Whites in the United States. Racial/ethnic variations in the incidence of stroke and prevalence of stroke risk factors are probably explained by both genetic and environmental influences. Family studies can help identify genetic predisposition to stroke and potential stroke precursors. Few studies have evaluated the heritability of these stroke risk factors among non-White populations, and none have focused on Caribbean Hispanic populations. The aim of the Northern Manhattan Family Study (NOMAFS) is to investigate the gene-environment interaction of stroke risk factors among Caribbean Hispanics. The unique recruitment and methodologic approaches used in this study are relevant to the design and conduct of genetic aggregation studies to investigate complex genetic disorders in non-White populations. The aim of this paper is to describe the NOMAFS and report enrollment and characteristics of the participants. The NOMAFS will provide a data resource for the exploration of the genetic determinants of highly heritable stroke precursor phenotypes that are less complex than the stroke phenotype. Understanding the gene environment interaction is the critical next step toward the development of new and unique approaches to disease prevention and interventions.
Indexed as
Identifiers
17682370PMC2556080W66410187What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.