ArticlePediatric nephrology (Berlin, Germany)2007
Antenatal and postnatal risk factors for neonatal hypertension and infant follow-up.
Article in Pediatric nephrology (Berlin, Germany), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 109 citations in OpenAlex.
- Systemic hypertension in very preterm infants: a population-based study.European journal of pediatrics · 2026Article
- Changes in cardiorespiratory status after transcatheter patent ductus arteriosus closure.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Postnatal Changes of Renin and Aldosterone in Term and Preterm Infants from Birth to Day 5.Biomedicines · 2025Article
- Neonatal intermittent hypoxemia events are associated with later systemic hypertension.Pediatric research · 2025Article
- Dosing trajectories of antihypertensive agents among preterm neonates: A retrospective, cross-sectional analysis.PloS one · 2025Article
- Cardiovascular Sequelae of Bronchopulmonary Dysplasia in Preterm Neonates Born before 32 Weeks of Gestational Age: Impact of Associated Pulmonary and Systemic Hypertension.Journal of cardiovascular development and disease · 2024Review
- Review
- Blood Pressure Outcomes in NICU-Admitted Infants with Neonatal Hypertension: A Pediatric Nephrology Research Consortium Study.The Journal of pediatrics · 2024Article
- Normative values of renin and aldosterone in clinically stable preterm neonates.Pediatric nephrology (Berlin, Germany) · 2023Article
- Neonatal hypertension: concerns within and beyond the neonatal intensive care unit.Clinical and experimental pediatrics · 2022Article
- Systemic Hypertension in Infants with Bronchopulmonary Dysplasia.Current hypertension reports · 2022Review
- Safety, Feasibility, and Impact of Enalapril on Cardiorespiratory Physiology and Health in Preterm Infants with Systemic Hypertension and Left Ventricular Diastolic Dysfunction.Journal of clinical medicine · 2021Article
- Article
- Assessment of the Cardiovascular Risk Profile of Infants Exposed to Pre-eclampsiaFrontiers in cardiovascular medicine · 2021Article
- The changing spectrum of hypertension in premature infants.Journal of perinatology : official journal of the California Perinatal Association · 2019Article
- Pulmonary Function and Systolic Blood Pressure in Very Low Birth Weight Infants at 34 - 36 Weeks of Corrected Age.Research and reports in neonatology · 2019Article
- Phthalate-associated hypertension in premature infants: a prospective mechanistic cohort study.Pediatric nephrology (Berlin, Germany) · 2019Observational
- Neonatal hypertension: an educational review.Pediatric nephrology (Berlin, Germany) · 2019Review
- Neonatal hypertension: cases, causes, and clinical approach.Pediatric nephrology (Berlin, Germany) · 2019Review
- Hypertension secondary to renal hypoplasia presenting as acute heart failure in a newborn.Clinical hypertension · 2019Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neonatal hypertension is an uncommon but important complication of intensive care management. The aims of this study were to identify in neonates with hypertension: antenatal and postnatal risk factors; aldosterone and renin levels; and report on outcome in early infancy. The study involved a retrospective review of neonates diagnosed with systemic hypertension from January 2001 to December 2005. Demographic data, risk factors, laboratory investigation, and follow-up data at 3-6 months of age were collected. Of the 2,572 newborn infants included, 34 (1.3%) had neonatal hypertension. Gestational age and birth weight and length were significantly lower in infants with hypertension. The median postnatal age at diagnosis of systemic hypertension was 5.0 days. Antenatal steroid administration, maternal hypertension, umbilical arterial catheter, postnatal acute renal failure, patent ductus arteriosus, indomethacin treatment and chronic lung disease were associated with the development of neonatal hypertension [odds ratios (OR) 8.7, 3.8, 10.0, 51.8, 5.9, 5.7 and 7.7, respectively]. Elevated aldosterone and renin levels occurred in 60% and 33% but had normalised in the majority by 6 months of age. The majority of infants do not require treatment for hypertension by 6 months of age.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.