ArticleInternational urology and nephrology2007
Pediatric nephrology patients are overweight: 20 years' experience in a single Canadian tertiary pediatric nephrology clinic.
Article in International urology and nephrology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Childhood Obesity: Insight into Kidney Involvement.International journal of molecular sciences · 2023Review
- Associations of body mass index (BMI) and BMI change with progression of chronic kidney disease in children.Pediatric nephrology (Berlin, Germany) · 2023Article
- Is the prognosis of congenital single functioning kidney benign? A population-based study.Pediatric nephrology (Berlin, Germany) · 2021Article
- Longitudinal outcomes of body mass index in overweight and obese children with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2021Article
- Are there any new reliable markers to detect renal injury in obese children?Renal failure · 2018Article
- Diagnosis, treatment and prevention of pediatric obesity: consensus position statement of the Italian Society for Pediatric Endocrinology and Diabetology and the Italian Society of Pediatrics.Italian journal of pediatrics · 2018Review
- Hypertension in pediatric patients with chronic kidney disease: management challenges.International journal of nephrology and renovascular disease · 2017Review
- Impact of obesity on kidney function and blood pressure in children.World journal of nephrology · 2015Review
- Early markers of obesity-related renal injury in childhood.Pediatric nephrology (Berlin, Germany) · 2015Review
- Metabolic syndrome in children with chronic kidney disease and after renal transplantation.Pediatric nephrology (Berlin, Germany) · 2014Review
- Is obesity a risk factor for chronic kidney disease in children?Pediatric nephrology (Berlin, Germany) · 2013Review
- Big mother or small baby: which predicts hypertension?Journal of clinical hypertension (Greenwich, Conn.) · 2011Article
- Cardiorespiratory fitness is a marker of cardiovascular health in renal transplanted children.Pediatric nephrology (Berlin, Germany) · 2010Article
- Body size in children with chronic kidney disease after gastrostomy tube feeding.Pediatric nephrology (Berlin, Germany) · 2010Article
- Postnatal assessment of growth, nutrition, and urinary tract infections of infants with antenatally detected hydronephrosis.International urology and nephrology · 2010Article
- Should prevention of chronic kidney disease start before pregnancy?International urology and nephrology · 2008Article
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6 authors.
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Abstract
backgroundObesity is an independent risk factor for chronic kidney disease (CKD). We compared the body composition of pediatric nephrology patients with that of the general child population over 2 decades.
methodsAbout 4,959 patients above 2 years of age (mean: 9.6 +/- 4.5) were referred to a tertiary pediatric nephrology clinic from 1985 to 2006. In 3,422 patients (69.0% with the same mean age) there were sufficient data to analyze body composition, expressed as body mass index (BMI) Z-score and calculated on the basis of normal data taken from the National (USA) Center for Health Statistics (2000).
resultsHematuria (21.68%), recurrent urinary tract infections (16.09%), proteinuria (13.95%) and hypertension (8.27%) were the most common referral diagnoses. Mean BMI Z-score of the pediatric nephrology patients increased significantly from 0.29 +/- 1.07 during the years 1985-1991 to 0.44 +/- 1.27 in 1992-1999 and 0.87 +/- 1.70 in 2000-2006 (P < 0.0001, ANOVA). Whereas the rate of the increase in BMI Z-score was not statistically different from that seen in the normal population, the young nephrology patients had over the entire time consistently significantly higher BMI Z-scores (average +0.72) than the comparable normal USA data. Several disease groups with potential for development of CKD had higher BMI Z-scores than found in the age- and sex-adjusted control data.
conclusionsThe increased rate of obesity in our studied population suggests that pediatric nephrology patients are at even greater risk for developing CKD later in life than could be predicted from their renal disease only. We recommend therapeutic intervention to address this potentially modifiable risk factor.
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