ArticleHypertension (Dallas, Tex. : 1979)2008
Pulsatile but not steady component of blood pressure predicts cardiovascular events in coronary patients.
Article in Hypertension (Dallas, Tex. : 1979), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 75 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Study of the Effects of Dapagliflozin on Ambulatory Aortic Pressure, Arterial Stiffness and Urine Albumin Excretion in Patients With Type 2 Diabetes
Comparison of Peripheral and Cerebral Arterial Flow in Acute Ischemic Stroke: Fimasartan vs. Valsartan vs. Atenolol
Who cites it
75 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The International Database of Central Arterial Properties for Risk Stratification: Research Objectives and Baseline Characteristics of Participants.American journal of hypertension · 2022Pooled it
- I Luso-Brazilian Positioning on Central Arterial Pressure.Arquivos brasileiros de cardiologia · 2017Guideline
- Recommendations for Improving and Standardizing Vascular Research on Arterial Stiffness: A Scientific Statement From the American Heart Association.Hypertension (Dallas, Tex. : 1979) · 2015Guideline
- Meta-analysis of the comparative effects of different classes of antihypertensive agents on brachial and central systolic blood pressure, and augmentation index.British journal of clinical pharmacology · 2013Pooled it
- Effect of Very Low-Intensity Resistance Exercise on Aortic-Brachial Blood Pressure Disparity in Young Men.American journal of hypertension · 2026Trial
- Trial
- Central blood pressure for the management of hypertension: Is it a practical clinical tool in current practice?Journal of clinical hypertension (Greenwich, Conn.) · 2020Trial
- Effect of supine versus sitting position on noninvasive assessment of aortic pressure waveform: a randomized cross-over study.Journal of human hypertension · 2014Trial
- Effects of aliskiren- and ramipril-based treatment on central aortic blood pressure in elderly with systolic hypertension: a substudy of AGELESS.Vascular health and risk management · 2014Trial
- Associations between pulse pressure amplification and inflammation in young adults according to body composition: The African-PREDICT study.Journal of human hypertension · 2026Article
- A Mediterranean-Style Diet with Lean Beef Lowers Blood Pressure and Improves Vascular Function: Secondary Outcomes from a Randomized Crossover Trial.Current developments in nutrition · 2025Article
- Determinant factors of the longitudinal pulse pressure among hypertensive patients treated at Assosa general hospital, Western Ethiopia.BMC cardiovascular disorders · 2024Article
- Invasively Measured Aortic Systolic Blood Pressure and Office Systolic Blood Pressure in Cardiovascular Risk Assessment in CKD.Kidney international reports · 2024Article
- The Efficacy of Single-pill Combination of Olmesartan Medoxomil and Amlodipine Besylate on Office Blood Pressure in Hypertensive Patients who did not Respond to Amlodipine Besylate Monotherapy.Electrolyte & blood pressure : E & BP · 2023Article
- Article
- Invasive validation of the Antares algorithm for determining central blood pressure based on upper arm oscillometric pulse waves in patients with type 2 diabetes.BMJ open diabetes research & care · 2023Article
- Integrative physiological assessment of cerebral hemodynamics and metabolism in acute ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Review
- Associations between measurements of central blood pressure and target organ damage in high-risk patients.Clinical hypertension · 2021Article
- Association of free fatty acid binding protein with central aortic stiffness, myocardial dysfunction and preserved ejection fraction heart failure.Scientific reports · 2021Article
- Exercise Intolerance in Heart Failure With Preserved Ejection Fraction: Arterial Stiffness and Aabnormal Left Ventricular Hemodynamic Responses During Exercise.Journal of cardiac failure · 2021Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the differences between central and peripheral blood pressure (BP) values have been known for decades, the consequences of decision making based on peripheral rather than central BP have only recently been recognized. There are only a few studies assessing the relationship between intraaortic BP and cardiovascular risk. In addition, the relationship between central BP and the risk of cardiovascular events in a large group of coronary patients has not yet been evaluated. Therefore, the aim of the study was to determine the prognostic significance of central BP-derived indices in patients undergoing coronary angiography. Invasive central BPs were taken at baseline, and study end points were ascertained during over a 4.5-year follow-up in 1109 consecutive patients. The primary end point (cardiovascular death or myocardial infarction or stroke or cardiac arrest or heart transplantation or myocardial revascularization) occurred in 246 (22.2%) patients. Central pulsatility was the most powerful predictor of the primary end point (hazard ratio [HR] 1.30, 95% confidence interval [CI] 1.14 to 1.48). Central pulse pressure was also independently related to the primary end point (HR 1.25, 95% CI 1.09 to 1.43). Central mean BP as well as peripheral BP parameters were not independently related to the primary end point risk. Central pulsatility was also related to risk of cardiovascular death or myocardial infarction or stroke. The pulsatile component of BP is the most important factor related to the cardiovascular risk in coronary patients. It is more closely associated with cardiovascular risk than steady component of BP.
Indexed as
Identifiers
18268136What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.