Evidence map›Paper›PMID 18373328›Full record

ReviewClinical cardiology2007

The pathophysiology of chronic ischemic heart disease.

Carl J Pepine, Wilmer W Nichols

Abstract readReview
In one paragraph

Review in Clinical cardiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Advances in Nitric Oxide-Releasing Hydrogels for Biomedical Applications.Current opinion in colloid & interface science · 2023
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  18. Arterial Stiffness, Central Pulsatile Hemodynamic Load, and Orthostatic Hypotension.Journal of clinical hypertension (Greenwich, Conn.) · 2016
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Carl J PepineDivision of Cardiovascular Medicine, Gainesville, FL 32610-0277, USA. pepincj@medicine.ufl.edu
Wilmer W Nichols

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With our success in management of acute coronary syndromes (ACS), aging population and epidemics of diabetes and obesity, the management of patients with chronic coronary artery disease is becoming an increasing important part of clinical practice. Although the rates of death and myocardial infarction (MI) in this group of patients are not high as a group, a subgroup has very high risk but many have poor quality of life related to limiting angina. The purpose of this article is to review the pathophysiology of the chronic angina syndrome to provide an improved understanding of the basis for the comprehensive management required to yield patient benefits. Where possible, targets for novel therapeutic approaches are highlighted.

Indexed as

AnemiaAngina PectorisChronic DiseaseCoronary Artery DiseaseCoronary CirculationCoronary ThrombosisCoronary VesselsEndothelium, VascularHeartHumansMuscle, Smooth, VascularMyocardial IschemiaMyocardiumOxygenOxygen

Identifiers

PMID18373328
PMCPMC6653055

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.