ArticleEuropean radiology2008
Characterization of coronary atherosclerosis by dual-source computed tomography and HU-based color mapping: a pilot study.
Article in European radiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A meta analysis and hierarchical classification of HU-based atherosclerotic plaque characterization criteria.PloS one · 2013Pooled it
- Effect of icosapent ethyl on progression of coronary atherosclerosis in patients with elevated triglycerides on statin therapy: final results of the EVAPORATE trial.European heart journal · 2020Trial
- The Cardiovascular Trial of the Testosterone Trials: rationale, design, and baseline data of a clinical trial using computed tomographic imaging to assess the progression of coronary atherosclerosis.Coronary artery disease · 2016Trial
- Implications of coronary calcification on the assessment of plaque pathology: a comparison of computed tomography and multimodality intravascular imaging.European radiology · 2025Article
- Using artificial intelligence to study atherosclerosis from computed tomography imaging: A state-of-the-art review of the current literature.Atherosclerosis · 2024Review
- High-quality annotations for deep learning enabled plaque analysis in SCAPIS cardiac computed tomography angiography.Heliyon · 2023Article
- Intravascular imaging of angioplasty balloon under-expansion during pre-dilation predicts hyperelastic behavior of coronary artery lesions.Frontiers in bioengineering and biotechnology · 2023Article
- Assessment of the correlation between arterial lumen density and its metabolic activity in atherosclerotic patients usingAmerican journal of nuclear medicine and molecular imaging · 2023Article
- A Novel Classification for Predicting Chronic Total Occlusion Percutaneous Coronary Intervention.Frontiers in cardiovascular medicine · 2022Article
- Elevated Serum Levels of Soluble ST2 Are Associated With Plaque Vulnerability in Patients With Non-ST-Elevation Acute Coronary Syndrome.Frontiers in cardiovascular medicine · 2021Article
- Association of High-Density Calcified 1K Plaque With Risk of Acute Coronary Syndrome.JAMA cardiology · 2020Article
- Comprehensive Modeling and Visualization of Cardiac Anatomy and Physiology from CT Imaging and Computer Simulations.IEEE transactions on visualization and computer graphics · 2017Article
- Dynamic change of high-risk plaque detected by coronary computed tomographic angiography in patients with subclinical coronary artery disease.The international journal of cardiovascular imaging · 2016Article
- Noninvasive diagnosis of vulnerable coronary plaque.World journal of cardiology · 2016Review
- Correction of lumen contrast-enhancement influence on non-calcified coronary atherosclerotic plaque quantification on CT.The international journal of cardiovascular imaging · 2015Article
- A novel method for non-invasive plaque morphology analysis by coronary computed tomography angiography.The international journal of cardiovascular imaging · 2014Article
- Characterization of atherosclerotic plaque: a contrast-detail study using multidetector and cone-beam computed tomography.Journal of applied clinical medical physics · 2014Article
- The effect of iterative reconstruction on quantitative computed tomography assessment of coronary plaque composition.The international journal of cardiovascular imaging · 2014Article
- Automatic quantification and characterization of coronary atherosclerosis with computed tomography coronary angiography: cross-correlation with intravascular ultrasound virtual histology.The international journal of cardiovascular imaging · 2013Article
- Computed tomography angiography-guided percutaneous coronary intervention in chronic total occlusion.Journal of Zhejiang University. Science. B · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
To assess HU-based color mapping for characterization of coronary plaque, using intravascular ultrasound virtual histology (IVUS-VH) as a standard of reference. Dual-source computed tomography and IVUS-VH were prospectively performed in 13 patients. In five lesions, HU thresholds of the color-coding software were calibrated to IVUS-VH. In a 15-lesion verification cohort, volumes of vessel, lumen and plaque or percentages of lipid, fibrous and calcified components were obtained through use of pre-set HU cut-offs as well as through purely visual adjustment of color maps. Calibrated HU ranges for fatty or fibrous plaque, lumen and calcification were -10-69, 70-158, 159-436 and 437+. Using these cut-offs, HU-based analysis achieved good agreement of plaque volume with IVUS (47.0 vs. 51.0 mm(3)). Visual segmentation led to significant overestimation of atheroma (61.6 vs. 51.0 mm(3); P = 0.04) Correlation coefficients for volumes of vessel, lumen and plaque were 0.92, 0.87 and 0.83 with HU-based analysis or 0.92, 0.85 and 0.71 with visual evaluation. With both methods, correlation of percentage plaque composition was poor or insignificant. HU-based plaque analysis showed good reproducibility with intra-class correlation coefficients being 0.90 for plaque volume and 0.81, 0.94 or 0.98 for percentages of fatty, fibrous or calcified components. With use of optimized HU thresholds, color mapping allows for accurate and reproducible quantification of coronary plaque.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.