Evidence mapPaperPMID 18617080Full record

Trial reportAmerican journal of preventive medicine2008

Weight loss during the intensive intervention phase of the weight-loss maintenance trial.

Jack F Hollis, Christina M Gullion, Victor J Stevens, Phillip J Brantley, Lawrence J Appel, Jamy D Ard, Catherine M Champagne, Arlene Dalcin, Thomas P Erlinger, Kristine Funk and 7 more

2 registry-linked trialsAbstract readClinical Trial, Phase IRandomized Controlled Trial
In one paragraph

Trial report in American journal of preventive medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 154 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
154citing papers in PubMed, 11 pooled it
27.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04730557 nacompletednot on this mapstarted 2020, after this paper: background citation

Reducing Obesity and Cartilage Compression in Knees

TypeinterventionalSponsorDuke UniversityRan2020 to 2024Enrolled88ConditionsObesity, Osteoarthritis, Knee OsteoarthritisArmsWeight Loss
NCT06379802 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Lifestyle Intervention With Physical Activity and Diet for Precision Health in Individuals With Overweight: a 6-month Pilot Randomized Controlled Trial (LI-PAD)

TypeinterventionalSponsorVastra Gotaland RegionRan2024 to 2027Enrolled120ConditionsOverweightArmsIndividualized physical activity and diet
3 · Its place in the literature

Who cites it

154 citing papers in PubMed, 11 syntheses or guidelines pooled it, 321 citations in OpenAlex.

  1. Identifying Social Media-Based Interactions That Help Adults to Adhere to Weight Loss Goals: A Systematic Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Pooled it
  2. Effects of total diet replacement programs on mental well-being: A systematic review with meta-analyses.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
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  7. Family-focused physical activity, diet and obesity interventions in African-American girls: a systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2013
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  10. Weight loss and African-American women: a systematic review of the behavioural weight loss intervention literature.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2012
    Pooled it
  11. Self-monitoring in weight loss: a systematic review of the literature.Journal of the American Dietetic Association · 2011
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94 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 10 institutions in 1 country.

Jack F HollisCenter for Health Research, Kaiser Permanente Northwest, Portland, Oregon 97227, USA. jack.hollis@kpchr.org
Christina M Gullion
Victor J Stevens
Phillip J Brantley
Lawrence J Appel
Jamy D Ard
Catherine M Champagne
Arlene Dalcin
Thomas P Erlinger
Kristine Funk
Daniel Laferriere
Pao-Hwa Lin
Catherine M Loria
Carmen Samuel-Hodge
William M Vollmer
Laura P Svetkey
Weight Loss Maintenance Trial Research Group
Kaiser Permanente · USJohns Hopkins University · USDuke Medical Center · USDuke University · USKaiser Permanente Center for Health Research · USNational Institutes of Health · USPennington Biomedical Research Center · USUniversity of Alabama at Birmingham · USUniversity of North Carolina at Chapel Hill · USUniversity of Pennsylvania · US

Funding

WEIGHT LOSS MAINTENANCE TRIALU01HL068676 · KAISER FOUNDATION RESEARCH INSTITUTE · 2003 to 2005
$4.3M
WEIGHT LOSS MAINTENANCE TRIALU01HL068734 · DUKE UNIVERSITY · 2003 to 2005
$2.1M
WEIGHT LOSS MAINTENANCE TRIALU01HL068790 · KAISER FOUNDATION RESEARCH INSTITUTE · 2003 to 2005
$1.7M
WEIGHT LOSS MAINTENANCE TRIALU01HL068920 · JOHNS HOPKINS UNIVERSITY · 2003 to 2005
$1.6M
WEIGHT LOSS MAINTENANCE TRIALU01HL068955 · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · 2003 to 2005
$1.5M
NHLBI NIH HHS 5-HL68955NHLBI NIH HHS 5-U01 HL68676NHLBI NIH HHS 5-U01 HL68734NHLBI NIH HHS 5-U01 HL68790NHLBI NIH HHS 5-U01 HL68920NHLBI NIH HHS U01 HL068676NHLBI NIH HHS U01 HL068734NHLBI NIH HHS U01 HL068790NHLBI NIH HHS U01 HL068920NHLBI NIH HHS U01 HL068955
6 · The paper itself

Abstract

backgroundTo improve methods for long-term weight management, the Weight Loss Maintenance (WLM) trial, a four-center randomized trial, was conducted to compare alternative strategies for maintaining weight loss over a 30-month period. This paper describes methods and results for the initial 6-month weight-loss program (Phase I).

methodsEligible adults were aged > or =25, overweight or obese (BMI=25-45 kg/m2), and on medications for hypertension and/or dyslipidemia. Anthropomorphic, demographic, and psychosocial measures were collected at baseline and 6 months. Participants (n=1685) attended 20 weekly group sessions to encourage calorie restriction, moderate-intensity physical activity, and the DASH (dietary approaches to stop hypertension) dietary pattern. Weight-loss predictors with missing data were replaced by multiple imputation.

resultsParticipants were 44% African American and 67% women; 79% were obese (BMI> or =30), 87% were taking anti-hypertensive medications, and 38% were taking antidyslipidemia medications. Participants attended an average of 72% of 20 group sessions. They self-reported 117 minutes of moderate-intensity physical activity per week, kept 3.7 daily food records per week, and consumed 2.9 servings of fruits and vegetables per day. The Phase-I follow-up rate was 92%. Mean (SD) weight change was -5.8 kg (4.4), and 69% lost at least 4 kg. All race-gender subgroups lost substantial weight: African-American men (-5.4 kg +/- 7.7); African-American women (-4.1 kg +/- 2.9); non-African-American men (-8.5 kg +/- 12.9); and non-African-American women (-5.8 kg +/- 6.1). Behavioral measures (e.g., diet records and physical activity) accounted for most of the weight-loss variation, although the association between behavioral measures and weight loss differed by race and gender groups.

conclusionsThe WLM behavioral intervention successfully achieved clinically significant short-term weight loss in a diverse population of high-risk patients.

Indexed as

DietExerciseWeight LossAdultCombined Modality TherapyDiet RecordsFemaleHumansMaleMiddle AgedObesityOverweightPatient Compliance

Identifiers

PMID18617080
PMCPMC2515566
OpenAlexW2098371352

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.