Evidence map›Paper›PMID 18684237›Full record

ReviewJournal of cellular and molecular medicine2008

Mesenchymal stem cells and cardiac repair.

Catharina Nesselmann, Nan Ma, Karen Bieback, Wolfgang Wagner, Anthony Ho, Yrjö T Konttinen, Hao Zhang, Mihail E Hinescu, Gustav Steinhoff

Erratum issuedAbstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  16. Effects of CoCl2 on multi-lineage differentiation of C3H/10T1/2 mesenchymal stem cells.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2016
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4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

9 authors.

Catharina NesselmannDepartment of Cardiac Surgery, University of Rostock, Germany.
Nan Ma
Karen Bieback
Wolfgang Wagner
Anthony Ho
Yrjö T Konttinen
Hao Zhang
Mihail E Hinescu
Gustav Steinhoff

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating clinical and experimental evidence indicates that mesenchymal stem cells (MSCs) are promising cell types in the treatment of cardiac dysfunction. They may trigger production of reparative growth factors, replace damaged cells and create an environment that favours endogenous cardiac repair. However, identifying mechanisms which regulate the role of MSCs in cardiac repair is still at work. To achieve the maximal clinical benefits, ex vivo manipulation can further enhance MSC therapeutic potential. This review focuses on the mechanism of MSCs in cardiac repair, with emphasis on ex vivo manipulation.

Indexed as

Mesenchymal Stem Cell TransplantationAnimalsBone Morphogenetic ProteinsCell DifferentiationCells, CulturedExtracellular MatrixGenetic EngineeringHeart DiseasesHumansIntercellular Signaling Peptides and ProteinsMesenchymal Stem CellsMyocardiumMyocytes, CardiacNeovascularization, PhysiologicBone Morphogenetic ProteinsIntercellular Signaling Peptides and Proteins

Identifiers

PMID18684237
PMCPMC4506151

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.