Evidence map›Paper›PMID 18765727›Full record

ReviewInfection and immunity2008

Two-component signal transduction proteins as potential drug targets in medically important fungi.

Neeraj Chauhan, Richard Calderone

Abstract readReview
In one paragraph

Review in Infection and immunity, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Backbone and side‑chainBiomolecular NMR assignments · 2025
    Article
  3. Polypeptides TargetingJournal of fungi (Basel, Switzerland) · 2023
    Article
  4. Proteomics of Two Thermotolerant Isolates ofJournal of fungi (Basel, Switzerland) · 2021
    Article
  5. Article
  6. Methanolic Extract of the HerbPharmaceuticals (Basel, Switzerland) · 2020
    Article
  7. Review
  8. Adaptation to macrophage killing byFuture science OA · 2017
    Review
  9. The yeasts phosphorelay systems: a comparative view.World journal of microbiology & biotechnology · 2017
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Neeraj ChauhanGeorgetown University Medical Center, Department of Microbiology & Immunology, 3900 Reservoir Road NW, Washington, DC 20057, USA.
Richard Calderone

Funding

TWO-COMPONENT HISTIDINE KINASES OF CANDIDA ALBICANSR01AI043465 · NIAID · GEORGETOWN UNIVERSITY · PI CALDERONE, RICHARD ARTHUR · 2000 to 2009
$2.9M
RESPONSE REGULATOR GENE (CASSK1) OF CANDIDA ALBICANSR01AI047047 · NIAID · GEORGETOWN UNIVERSITY · PI CALDERONE, RICHARD ARTHUR · 2000 to 2004
$1.6M
Triazole hypersensitivity in Candida albicansR21AI076084 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI CHAUHAN, NEERAJ · 2008 to 2009
$428k
NIAID NIH HHS AI43465NIAID NIH HHS R01 AI043465NIAID NIH HHS R01 AI047047NIAID NIH HHS R01 AI47047NIAID NIH HHS R21 AI076084
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antifungal AgentsDrug DesignFungal ProteinsHumansMycosesSignal TransductionAntifungal AgentsFungal Proteins

Identifiers

PMID18765727
PMCPMC2573338

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.