ArticleJournal of virology2008
Within-host genetic diversity of endemic and emerging parvoviruses of dogs and cats.
Article in Journal of virology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 62 citations in OpenAlex.
- Molecular Characterization of a Feline Panleukopenia Virus Strain Isolated from a Dog with Clinical Gastroenteritis in Spain.Animals : an open access journal from MDPI · 2026Article
- The host phylogeny determines viral infectivity and replication across Staphylococcus host species.PLoS pathogens · 2023Article
- Old and Novel Enteric Parvoviruses of Dogs.Pathogens (Basel, Switzerland) · 2023Review
- Oncolytic Rodent Protoparvoviruses Evade a TLR- and RLR-Independent Antiviral Response in Transformed Cells.Pathogens (Basel, Switzerland) · 2023Article
- Low Intrahost and Interhost Genetic Diversity ofViruses · 2022Article
- First detection of feline bocaparvovirus 2 and feline chaphamaparvovirus in healthy cats in Turkey.Veterinary research communications · 2022Article
- Small but mighty: old and new parvoviruses of veterinary significance.Virology journal · 2021Review
- Molecular Analysis of Full-Length VP2 of Canine Parvovirus Reveals Antigenic Drift in CPV-2b and CPV-2c Variants in Central Chile.Animals : an open access journal from MDPI · 2021Article
- Detection of canine parvovirus and feline panleukopenia virus in fecal samples by strand exchange amplification.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2020Article
- Article
- Dynamic evolution of canine parvovirus in Thailand.Veterinary world · 2020Article
- Article
- Limited Intrahost Diversity and Background Evolution Accompany 40 Years of Canine Parvovirus Host Adaptation and Spread.Journal of virology · 2019Article
- Article
- Molecular Characterization and Evolutionary Analyses of Carnivore Protoparvovirus 1 NS1 Gene.Viruses · 2019Article
- Research on viral agents associated with feline reproductive problems reveals a high association with feline panleukopenia virus.Veterinary and animal science · 2018Article
- Article
- Molecular analysis of carnivore Protoparvovirus detected in white blood cells of naturally infected cats.BMC veterinary research · 2018Article
- Virome analysis for identification of novel mammalian viruses in bats from Southeast China.Scientific reports · 2017Article
- Isolation of Canine parvovirus with a view to identify the prevalent serotype on the basis of partial sequence analysis.Veterinary world · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Viral emergence can result from the adaptation of endemic pathogens to new or altered host environments, a process that is strongly influenced by the underlying sequence diversity. To determine the extent and structure of intrahost genetic diversity in a recently emerged single-stranded DNA virus, we analyzed viral population structures during natural infections of animals with canine parvovirus (CPV) or its ancestor, feline panleukopenia virus (FPV). We compared infections that occurred shortly after CPV emerged with more recent infections and examined the population structure of CPV after experimental cross-species transmission to cats. Infections with CPV and FPV showed limited genetic diversity regardless of the analyzed host tissue or year of isolation. Coinfections with genetically distinct viral strains were detected in some cases, and rearranged genomes were seen in both FPV and CPV. The sporadic presence of some sequences with multiple mutations suggested the occurrence of either particularly error-prone viral replication or coinfection by more distantly related strains. Finally, some potentially organ-specific host effects were seen during experimental cross-species transmission, with many of the mutations located in the nonstructural protein NS2. These included residues with evidence of positive selection at the population level, which is compatible with a role of this protein in host adaptation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.