Evidence map›Paper›PMID 18949106›Full record

Trial reportCanadian respiratory journal2008

Long-term compliance with continuous positive airway pressure in patients with obstructive sleep apnea.

Norman Wolkove, Marc Baltzan, Hany Kamel, Richard Dabrusin, Mark Palayew

3 registry-linked trialsOpen access · goldAbstract readClinical TrialComparative Study
In one paragraph

Trial report in Canadian respiratory journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 91 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01369576 phase3completednot on this mapstarted 2011, after this paper: background citation

A Double-blind, Randomized, Parallel Group Study to Determine the Effect of Initial Prescription of Zopiclone on the Level of Compliance With CPAP in Adult Patients Treated for OSA at 26 Weeks

TypeinterventionalSponsorOSR Medical Inc.Ran2011 to 2014Enrolled264ConditionsObstructive Sleep ApneaArmsPlacebo, Zopiclone
NCT02209220 nacompletednot on this mapstarted 2014, after this paper: background citation

Impact of Automatic Positive Airway Pressure on Treatment Compliance in Obstructive Sleep Apnea Patients Awaiting Bariatric Surgery

TypeinterventionalSponsorLaval UniversityRan2014 to 2018Enrolled50ConditionsObstructive Sleep Apnea, Treatment Compliance, Automatic Positive Airway PressureArmsPositive airway pressure for the treatment of OSA
NCT02781701 nawithdrawnnot on this mapstarted 2017, after this paper: background citation

Tongue Protrusion Force: A Pilot Study

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2017 to 2021Enrolled0ConditionsObstructive Sleep Apnea (OSA)ArmsTongue Trainer
3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 2 syntheses or guidelines pooled it, 202 citations in OpenAlex.

  1. Pooled it
  2. Reconsidering first-line treatment for obstructive sleep apnea: a systematic review of the literature.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2016
    Pooled it
  3. Trial
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  10. Efficacy of a novel oral appliance and the role of posture on nasal resistance in obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
    Trial
  11. Trial
  12. Trial
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  14. Long-term use of a nasal expiratory positive airway pressure (EPAP) device as a treatment for obstructive sleep apnea (OSA).Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2011
    Trial
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  16. A multicenter, prospective study of a novel nasal EPAP device in the treatment of obstructive sleep apnea: efficacy and 30-day adherence.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2009
    Trial
  17. Article
  18. Solid waste production by CPAP treatment in the United States.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Article
  19. A new method using pointing area diagrams to characterize and compare ventilation masks used in continuous positive airway pressure treatment for apneic patients.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  20. Impact of Postoperative Weight Changes on Hypoglossal Nerve Stimulation Success for Obstructive Sleep Apnea.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Article

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Norman WolkoveMount Sinai Hospital Centre, Montreal, Canada. norluco@yahoo.com
Marc Baltzan
Hany Kamel
Richard Dabrusin
Mark Palayew
Mount Sinai Hospital · CAMount Sinai Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundContinuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnea (OSA). However, compliance is a significant problem and has been incompletely assessed in long-term studies.

objectiveTo assess the long-term compliance of OSA patients with CPAP therapy. SUBJECTS: Eighty patients who had had a diagnosis of OSA at least four years previously and received a written prescription for CPAP were evaluated.

methodsSubjects were identified by reviewing sleep laboratory records. Participants were contacted by telephone and were asked to quantitate their CPAP use (hours per night, nights per week) and to evaluate whether there had been improvement in symptoms. Those who commenced but subsequently abandoned therapy and those who never initiated treatment were questioned about their reasons for noncompliance.

resultsPatient demographics included mean (+/- SD) age (58+/-11 years), male sex (70 of 80 patients [88%]) and mean apnea-hypopnea index (70+/-44 events/h). At the time of the interview (64.0+/-3.7 months after diagnosis), 43 of 80 patients (54%) were still using CPAP and most reported an improvement in symptoms. Twelve of 80 patients (15%) had abandoned CPAP after using it for 10.1+/-15.5 months, and 25 of 80 patients (31%) had never commenced therapy after initial diagnosis and CPAP titration. Analysis of scores reflecting initial patient sleepiness revealed a significant association of this symptom with subsequent CPAP compliance.

conclusionAlthough many patients with OSA derive subjective benefit from, and adhere to treatment with CPAP, a significant proportion of those so diagnosed either do not initiate or eventually abandon therapy. Initial experience with CPAP appears to be important, reinforcing the need for early education and support in these patients.

Indexed as

Continuous Positive Airway PressureFemaleFollow-Up StudiesHumansMaleMiddle AgedPatient ComplianceSleepSleep Apnea, ObstructiveSurveys and QuestionnairesTime FactorsTreatment Outcome

Identifiers

PMID18949106
PMCPMC2679572
OpenAlexW98015728

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.