Statins × lipids

TrialDiabetes care2009

Effects of high-dose simvastatin therapy on glucose metabolism and ectopic lipid deposition in nonobese type 2 diabetic patients.

Julia Szendroedi et al.PubMed ↗Full text ↗Publisher ↗

  • 80 mg simvastatinno clear effectLower plasma total cholesterol levels, no range given, lower plasma LDL cholesterol levels, no range given.No ranges given.

What the trial testedas reported · 2009

No range given

Reported lower plasma total cholesterol levels, no range given

−33.0

80 mg simvastatin vs placebo

As reported

difference −33.0, no interval

No range given

Reported lower plasma LDL cholesterol levels, no range given

−48.0percentage points

80 mg simvastatin vs placebo

As reported

difference −48.0 %, no interval

Who was studied, and how

people with dyslipidemia, in this paper

The trial randomly assignedassigned by chance

80 mg simvastatin
placebo

Reported lower plasma total cholesterol levels, no range given−33.0

Reported lower plasma LDL cholesterol levels, no range given−48.0

randomised

the abstract, start to end

LDL cholesterol levels by approximately 33 and approximately 48% (P < 0.005) but did not affect

← favours treatmentfavours comparator →
could be chance
No interval given · direction only, strength unknown
Plasma total cholesterol levels80 mg simvastatin vs placebo
−33.0
Plasma LDL cholesterol levels80 mg simvastatin vs placebo
−48.0
StatinsLipids
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Full record →Abstract, authors, funding and every citing paper · PMID 18957532