Evidence map›Paper›PMID 19229230›Full record

ArticleNature clinical practice. Endocrinology & metabolism2009

How effective is continuous glucose monitoring in intensively treated type 1 diabetes mellitus?

Joseph I Wolfsdorf

Abstract readComment
PubMed Publisher
In one paragraph

Article in Nature clinical practice. Endocrinology & metabolism, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Joseph I WolfsdorfDivision of Endocrinology, Children's Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA. joseph.wolfsdorf@childrens.harvard.edu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This Practice Point commentary discusses the findings of a multicenter clinical trial conducted by the Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Group. In the study, 322 individuals aged >/=8 years who were already receiving intensive insulin therapy for type 1 diabetes mellitus were randomly assigned to either a group that performed continuous glucose monitoring (CGM), or to a control group that performed conventional self-monitoring with a blood-glucose meter. At week 26, the between-group difference in the change in HbA(1c) level from baseline varied according to the patient's age. A significantly greater reduction in HbA(1c) level in the CGM group compared with the control group was found in patients aged >or=25 years, but not in those aged 8-14 years or 15-24 years. In patients aged >or=25 years, CGM improved glycemic control without increasing the frequency of hypoglycemia. Motivation, willingness to change diabetes self-care behaviors, and the ability to use CGM effectively are important determinants of whether this technology will improve glycemic control.

Identifiers

PMID19229230

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.