Metformin × lipids

TrialDiabete & metabolisme1991

The effects of oral hypoglycaemic drugs on serum lipids and lipoproteins in non-insulin-dependent diabetes (NIDDM).

R S ElkelesPubMed ↗

  • Metforminlooks good hereLower LDL cholesterol.Randomised, small.

What the trial testedrandomised · 35 people · 1991

Randomised vs glibenclamide

Probably lowered LDL cholesterol

−0.34−0.57 to −0.12

metformin vs glibenclamide

As reported

difference −0.34, 95% CI −0.57 to −0.12 · the paper's word: low density lipoprotein cholesterol

Who was studied, and how

35people with dyslipidemia, in this paper

The trial randomly assignedassigned by chance

metformin
glibenclamide

Probably lowered LDL cholesterol−0.34

randomised

the abstract, start to end

lipoprotein cholesterol (mean change -0.34 mmol/1.95% confidence intervals

← favours treatmentfavours comparator →
could be chance
Low density lipoprotein cholesterolmetformin vs glibenclamide
−0.34−0.57 to −0.12
MetforminLipids
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3 papers cite it

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Full record →Abstract, authors, funding and every citing paper · PMID 1936476