Is muscle the major site of insulin resistance in type 2 (non-insulin-dependent) diabetes mellitus?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed.

1. Pioglitazone decreases fasting and postprandial endogenous glucose production in proportion to decrease in hepatic triglyceride content.Diabetes · 2008
   Trial
2. Insulin secretion, insulin action, and hepatic glucose production in identical twins discordant for non-insulin-dependent diabetes mellitus.The Journal of clinical investigation · 1995
   Trial
3. Effects of low dose versus conventional dose thiazide diuretic on insulin action in essential hypertension.BMJ (Clinical research ed.) · 1994
   Trial
4. The KLF14 transcription factor regulates hepatic gluconeogenesis in mice.The Journal of biological chemistry · 2017
   Article
5. The role of the liver in type 2 diabetes.Reviews in endocrine & metabolic disorders · 2004
   Review
6. Is hepatic glucose production increased in type 2 diabetes mellitus?Current diabetes reports · 2002
   Review
7. Insulin resistance.BMJ (Clinical research ed.) · 1996
   Review
8. Insulin resistance in non-insulin-dependent diabetes mellitus. A review.Acta diabetologica · 1996
   Review
9. Multiple defects of both hepatic and peripheral intracellular glucose processing contribute to the hyperglycaemia of NIDDM.Diabetologia · 1995
   Article
10. Pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: the role of skeletal muscle glucose uptake and hepatic glucose production in the development of hyperglycaemia. A critical comment.Diabetologia · 1994
    Review
11. Pathogenesis of type 2 (non-insulin dependent) diabetes mellitus: a balanced overview.Diabetologia · 1992
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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