Evidence map›Paper›PMID 19482599›Full record

ReviewFrontiers in bioscience (Landmark edition)2009

RNA processing in the polyoma virus life cycle.

Yingqun Huang, Gordon G Carmichael

Open access · bronzeAbstract readReview
In one paragraph

Review in Frontiers in bioscience (Landmark edition), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yingqun HuangDepartment of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, 300 George Street, New Haven, CT 06511, USA.
Gordon G Carmichael
Yale University · US

Funding

PROCESSING AND FUNCTION OF POLYOMA RNAR01CA045382 · NCI · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI CARMICHAEL, GORDON G · 1987 to 2015
$4.7M
NCI NIH HHS CA04382NCI NIH HHS R01 CA045382
6 · The paper itself

Abstract

Not only is gene regulation in polyoma interesting, but it has also proven to be highly informative and illustrative of a number of novel concepts in gene regulation. Of special interest and importance are the mechanisms by which this virus switches from the expression of early gene products to late gene products after the onset of viral DNA replication. This switch is mediated at least in part by changes in transcription elongation and polyadenylation in the late region, and by the formation and editing of dsRNA in the nucleus. In this review we will summarize the regulation of RNA synthesis and processing during polyoma infection, and will point out in particular those aspects that have been most novel.

Indexed as

AnimalsBase SequenceDNA, ViralGene Expression Regulation, ViralGenome, ViralMiceMolecular Sequence DataPolyomavirusPromoter Regions, GeneticRNA, MessengerRNA Processing, Post-TranscriptionalRNA SplicingRNA, ViralDNA, ViralRNA, MessengerRNA, Viral

Identifiers

PMID19482599
PMCPMC4097024
OpenAlexW2016009151

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.