Evidence mapPaperPMID 19490820Full record

ReviewCurrent diabetes reports2009

Pathophysiology of prediabetes.

Muhammad A Abdul-Ghani, Ralph A DeFronzo

3 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Current diabetes reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 80 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03658031 phase3unknown statusstarted 2019, after this paper: background citation

Effect of Dapagliflozin on the Progression From Prediabetes to T2DM in Subjects With Myocardial Infarction

Ran2019Enrolled576Registered outcomes1Posted comparisons0ConditionsCVD, Myocardial Infarction, Prediabetes, T2DM (Type 2 Diabetes Mellitus)ArmsDapagliflozin 10mg
Open the trial in the graph
NCT03325933 naterminatednot on this mapstarted 2017, after this paper: background citation

Resistance Training and Cardiometabolic Health

TypeinterventionalSponsorArizona State UniversityRan2017 to 2020Enrolled62ConditionsInsulin Sensitivity, Endothelial Dysfunction, Blood PressureArmsHigh Load/Low Rep Resistance Training, Low Load/High Rep Resistance Training
NCT04268862 unknown statusnot on this mapstarted 2020, after this paper: background citation

Ethnic Dependence of the Metabolic Defects in Prediabetic Individuals: Kuwaiti Arabs Versus Indians

TypeobservationalSponsorDasman Diabetes InstituteRan2020 to 2021Enrolled120ConditionsPathophysiology, Metabolic Glucose Disorders
3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 1 synthesis or guideline pooled it, 147 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Insulin resistance, CaFrontiers in physiology · 2025
    Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Muhammad A Abdul-GhaniDiabetes Division, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA. abdulghani@uthscsa.edu
Ralph A DeFronzo
Texas Diabetes Institute · USThe University of Texas Health Science Center at San Antonio · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The term prediabetes refers to subjects with impaired fasting glucose and/or impaired glucose tolerance who are at increased risk for type 2 diabetes mellitus. Although both types of patients are at increased risk for developing type 2 diabetes mellitus and cardiovascular disease, they manifest distinct metabolic abnormalities. In this article, we summarize the metabolic abnormalities that characterize each state and the contribution of these metabolic abnormalities to the increased risk of diabetes and cardiovascular disease.

Indexed as

Blood GlucoseCardiovascular DiseasesDiabetes Mellitus, Type 2Glucose IntoleranceHumansInsulinInsulin ResistancePrediabetic StateBlood GlucoseInsulin

Identifiers

PMID19490820
OpenAlexW2109356083

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.