Evidence map›Paper›PMID 19734396›Full record

Trial reportJournal of the American Board of Family Medicine : JABFM

Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial.

Paul Crawford

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of the American Board of Family Medicine : JABFM. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It reports registered trial NCT05343767. Cited by 87 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05343767 nacompleted

A Phase II, Randomized, Double Blind, Double Dummy, Active-Controlled Clinical Trial to Investigate the Efficacy and Safety of Low-Glu in Patients Newly Diagnosed With Type II Diabetes Mellitus

Ran2018Enrolled198Registered outcomes6Posted comparisons0ConditionsType2 Diabetes MellitusArmsMetformin, Natural Wellness Low-Glu high dose, Natural Wellness Low-Glu low dose
PMID 9506190PMID 9686693PMID 19875552PMID 19896746PMID 33298420PMID 11742409PMID 18066129PMID 18672036PMID 18801863PMID 19464860PMID 19699773PMID 30873688other papers from this trial
Open the trial in the graph
NCT04023539 nacompletednot on this map

Evaluation of the Effect of Cinnamomum Zeylanicum on Glycemic Levels of Mexican Adult Patients With Type 2 Diabetes at 3 Months: Randomized Clinical Trial

TypeinterventionalSponsorUniversidad de SonoraRan2019 to 2020Enrolled30ConditionsType 2 DiabetesArmsCinnamomum zeylanicum, Placebo
3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  7. Cinnamon for diabetes mellitus.The Cochrane database of systematic reviews · 2012
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  8. Ayurvedic treatments for diabetes mellitus.The Cochrane database of systematic reviews · 2011
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27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Paul CrawfordNellis Family Medicine Residency, Mike O'Callaghan Federal Hospital, Las Vegas, NV 89191, USA. paul.crawford@nellis.af.mil

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMultiple trials in the past have shown conflicting results of whether cinnamon lowers glucose or hemoglobin A1C (HbA1C). The purpose of this study was to determine whether cinnamon lowers HbA1C in patients with type 2 diabetes. I performed a randomized, controlled trial to evaluate whether daily cinnamon plus usual care versus usual care alone lowers HbA1c.

methodsI randomized 109 type 2 diabetics (HbA1C >7.0) from 3 primary care clinics caring for pediatric, adult, and geriatric patients at a United States military base. Participants were randomly allocated to either usual care with management changes by their primary care physician or usual care with management changes plus cinnamon capsules, 1g daily for 90 days. HbA1c was drawn at baseline and 90 days and compared with intention-to-treat analysis. This study was approved by an institutional review board.

resultsCinnamon lowered HbA1C 0.83% (95% CI, 0.46-1.20) compared with usual care alone lowering HbA1C 0.37% (95% CI, 0.15-0.59).

conclusionsTaking cinnamon could be useful for lowering serum HbA1C in type 2 diabetics with HbA1C >7.0 in addition to usual care.

Indexed as

AgedCinnamomum zeylanicumDiabetes Mellitus, Type 2FemaleFloridaGlycated HemoglobinHumansMaleMiddle AgedTreatment OutcomeGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID19734396

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.