ReviewCurrent topics in medicinal chemistry2010
Template-based protein modeling: recent methodological advances.
Review in Current topics in medicinal chemistry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed.
- Protein Structure Prediction Methods.Advances in experimental medicine and biology · 2026Review
- Challenges of Protein-Protein Docking of the Membrane Proteins.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Targeted Therapy with a Novel Superantigen-based Fusion Protein Against Interleukin-13 Receptor α2-overexpressing Tumor Cells: An In-silico Study.Iranian journal of pathology · 2024Article
- Ten quick tips for homology modeling of high-resolution protein 3D structures.PLoS computational biology · 2020Article
- Ligand-Binding-Site Structure Refinement Using Molecular Dynamics with Restraints Derived from Predicted Binding Site Templates.Journal of chemical theory and computation · 2019Article
- Molecular Docking: Shifting Paradigms in Drug Discovery.International journal of molecular sciences · 2019Review
- Adenoviral E4 34K protein interacts with virus packaging components and may serve as the putative portal.Scientific reports · 2017Article
- Modeling, molecular docking, probing catalytic binding mode of acetyl-CoA malate synthase G inBiochemistry and biophysics reports · 2016Article
- Protein structure prediction provides comparable performance to crystallographic structures in docking-based virtual screening.Methods (San Diego, Calif.) · 2015Article
- ModBase, a database of annotated comparative protein structure models and associated resources.Nucleic acids research · 2014Article
- Database resources for the tuberculosis community.Tuberculosis (Edinburgh, Scotland) · 2013Review
- Bioinformatics and variability in drug response: a protein structural perspective.Journal of the Royal Society, Interface · 2012Review
- BCL::Fold--de novo prediction of complex and large protein topologies by assembly of secondary structure elements.PloS one · 2012Article
- From laptop to benchtop to bedside: structure-based drug design on protein targets.Current pharmaceutical design · 2012Review
- Adapting Poisson-Boltzmann to the self-consistent mean field theory: application to protein side-chain modeling.The Journal of chemical physics · 2011Article
- TASSER_WT: a protein structure prediction algorithm with accurate predicted contact restraints for difficult protein targets.Biophysical journal · 2010Article
- Computational model of hepatitis B virus DNA polymerase: molecular dynamics and docking to understand resistant mutations.Protein science : a publication of the Protein Society · 2010Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Protein modeling has been a very challenging problem in drug discovery and computational biology. The latest advances and progress in computational power have helped to solve this problem to a considerable extent; however, predicting accurate three-dimensional structure of proteins has always been and remains a complicated assignment. Of the two common methods of protein structure prediction, template-based modeling has become more popular than ab initio modeling. In this review, we summarize the developments in methodology and of understanding for comparative protein modeling during the last three years, including for homologue search, fold recognition, secondary structure prediction, model building, loop building, side-chain prediction and model quality assessment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.