Evidence mapPaperPMID 20124137Full record

ReviewCirculation2010

Combination antithrombotic therapies.

Paul A Gurbel, Udaya S Tantry

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Circulation, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06675994 (Evaluation of PCSK9 Enzyme in Non-Cholesterol Biological Pathways), which is not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06675994 not yet recruitingstarted 2024, after this paper: background citation

Evaluation of PCSK9 Enzyme in Non-Cholesterol Biological Pathways: In Vitro Demonstration of Direct Platelet-Related Effects of PCSK9 Enzyme

Ran2024Enrolled80Registered outcomes4Posted comparisons0ConditionsDiabetes, Family History of Cerebrovascular Disease, Family History of Coronary Artery Disease, Family History of Peripheral Artery DiseaseArmsPCSK9 Antibody, PCSK9 Enzyme
Open the trial in the graph
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. An Insight into Recent Advances on Platelet Function in Health and Disease.International journal of molecular sciences · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Consensus Document ANMCO/ANCE/ARCA/GICR-IACPR/GISE/SICOA: Long-term Antiplatelet Therapy in Patients with Coronary Artery Disease.European heart journal supplements : journal of the European Society of Cardiology · 2018
    Article
  15. Article
  16. Article
  17. Article
  18. Novel antiplatelet agents in cardiovascular medicine.Current treatment options in cardiovascular medicine · 2015
    Article
  19. Review
  20. G-protein-coupled receptors signaling pathways in new antiplatelet drug development.Arteriosclerosis, thrombosis, and vascular biology · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Paul A GurbelSinai Center for Thrombosis Research, Cardiac Catheterization Laboratories, Sinai Hospital of Baltimore, 2401 W Belvedere Ave, Baltimore, MD 21215, USA. purbel@lifebridgehealth.org
Udaya S Tantry

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AspirinAtherosclerosisClopidogrelDrug Therapy, CombinationFibrinolytic AgentsHumansPyridinesThrombosisTiclopidineAspirinClopidogrelFibrinolytic AgentsPyridinesthienopyridineTiclopidine

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.