ReviewDrugs & aging2009
Development of CRIteria to assess appropriate Medication use among Elderly complex patients (CRIME) project: rationale and methodology.
Review in Drugs & aging, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Hand Grip Strength May Affect the Association Between Anticholinergic Burden and Mortality Among Older Patients Discharged from Hospital.Drugs & aging · 2020Trial
- Predictive Strategies to Reduce the Risk of Rehospitalization with a Focus on Frail Older Adults: A Narrative Review.Epidemiologia (Basel, Switzerland) · 2023Review
- Physical performance measures and hospital outcomes among Italian older adults: results from the CRIME project.Aging clinical and experimental research · 2021Observational
- Prognosis and Interplay of Cognitive Impairment and Sarcopenia in Older Adults Discharged from Acute Care Hospitals.Journal of clinical medicine · 2019Article
- Association of Anticholinergic Drug Burden with Cognitive and Functional Decline Over Time in Older Inpatients: Results from the CRIME Project.Drugs & aging · 2018Article
- Anticholinergic burden and health outcomes among older adults discharged from hospital: results from the CRIME study.European journal of clinical pharmacology · 2017Article
- Polypharmacy and inappropriate medication use in patients with dementia: an underresearched problem.Therapeutic advances in drug safety · 2017Review
- Functional changes during hospital stay in older patients admitted to an acute care ward: a multicenter observational study.PloS one · 2014Observational
- Recommendations to prescribe in complex older adults: results of the CRIteria to assess appropriate Medication use among Elderly complex patients (CRIME) project.Drugs & aging · 2014Review
- Physical performance measures and polypharmacy among hospitalized older adults: results from the CRIME study.The journal of nutrition, health & aging · 2014Article
- [Suitability of pharmacological treatment in patients with multiple chronic conditions].Atencion primaria · 2013Review
- Adverse drug reactions in older people: detection and prevention.Drugs & aging · 2012Review
- Evidence-based strategies for the optimization of pharmacotherapy in older people.Drugs & aging · 2012Review
- Inappropriate drugs in elderly patients with severe cognitive impairment: results from the shelter study.PloS one · 2012Article
- Estimating renal function to reduce the risk of adverse drug reactions.Drug safety · 2012Review
- Explicit criteria for potentially inappropriate medications to reduce the risk of adverse drug reactions in elderly people: from Beers to STOPP/START criteria.Drug safety · 2012Review
- Multiple diseases and polypharmacy in the elderly: challenges for the internist of the third millennium.Journal of comorbidity · 2011Review
- Iatrogenic disease in the elderly: risk factors, consequences, and prevention.Clinical interventions in aging · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pharmacological treatment of complex older adults with comorbidities, multiple impairments in function, cognition, social status and geriatric syndromes represents a challenge for prescribing physicians and often results in a high rate of iatrogenic illnesses. Clinical guidelines are commonly used to indicate appropriate prescription, but they are often based on the results of clinical trials that are conducted on young subjects with a low level of complexity. Therefore, the recommendations of clinical guidelines may be difficult to apply to older complex adults. In this paper we present the rationale and methodology of the Development of CRIteria to assess appropriate Medication use among Elderly complex patients (CRIME) project, a study aimed at producing recommendations to evaluate the appropriateness of pharmacological prescription in older complex patients, translating the recommendations of clinical guidelines to this type of patient. A literature search will be performed to integrate and revise the recommendations of disease-specific guidelines on the pharmacological treatment of patients with common chronic conditions. New recommendations will be provided and approved in a consensus meeting of international experts. Both data from randomized controlled trials and observational studies will be used to meet this aim. Recommendations provided by the CRIME project are not meant to replace existing clinical guidelines, but they may be used to help physicians in the prescribing process. Once completed these recommendations should be validated in interventional studies.
Indexed as
Identifiers
20136165What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.