Evidence map›Paper›PMID 20169408›Full record

ArticleInternational urology and nephrology2010

New-onset diabetes after transplantation in tacrolimus-treated, living kidney transplantation: long-term impact and utility of the pre-transplant OGTT.

Shoichi Iida, Hideki Ishida, Tadahiko Tokumoto, Kazuya Omoto, Hiroki Shirakawa, Tomokazu Shimizu, Hiroyuki Amano, Kiyoshi Setoguchi, Taiji Nozaki, Daisuke Toki and 2 more

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in International urology and nephrology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05316038 (Study of the Impact of Belatacept Conversion on Metabolic and Infectious Complications in Kidney Transplant Recipients at Grenoble-Alpes University Hospital), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05316038 unknown statusnot on this mapstarted 2022, after this paper: background citation

Study of the Impact of Belatacept Conversion on Metabolic and Infectious Complications in Kidney Transplant Recipients at Grenoble-Alpes University Hospital

TypeobservationalSponsorUniversity Hospital, GrenobleRan2022 to 2024Enrolled100ConditionsKidney Transplant Infection, Cardiovascular Diseases, Immunosuppression, Kidney TransplantArmsOral glucose tolerance test
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Shoichi IidaSection of Renal Transplantation/Renovascular Surgery, Tokyo Women's Medical University, Tokyo, Japan. sho.i@f4.dion.ne.jp
Hideki Ishida
Tadahiko Tokumoto
Kazuya Omoto
Hiroki Shirakawa
Tomokazu Shimizu
Hiroyuki Amano
Kiyoshi Setoguchi
Taiji Nozaki
Daisuke Toki
Daisuke Tokita
Kazunari Tanabe
Tokyo Women's Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the role of the oral glucose tolerance test (OGTT) before transplantation and to examine the risk factors for new-onset diabetes after transplantation (NODAT) during long-term follow-up of renal transplant recipients receiving FK-based therapy.

methodsThe study evaluated 378 patients pre-transplantation using the OGTT and assigned them to one of three groups: Group 1, normal pattern; Group 2, impaired fasting glucose (IFG)/impaired glucose tolerance (IGT) pattern (IFG/IGT); and Group 3, DM pattern.

resultsAlthough the incidence of NODAT was higher in Group 3 than in groups 1 and 2, no significant difference was found between the three groups with regard to graft survival during long-term follow-up. Multivariate analysis showed that only a family history of diabetes was a significant factor determining NODAT progression.

conclusionsImpaired glucose tolerance appears to be a threshold influencing NODAT; however, it was not a significant factor in graft survival. Careful monitoring and management based on the result of the pre-transplantation OGTT appear to prevent the deterioration of impaired glucose tolerance in renal transplant recipients receiving FK-based therapy, even when a pre-operative OGTT shows impaired glycemic control.

Indexed as

Kidney TransplantationAdultDiabetes MellitusFemaleGlucose Tolerance TestHumansImmunosuppressive AgentsMaleMiddle AgedPreoperative CareRetrospective StudiesTacrolimusTime FactorsYoung AdultImmunosuppressive AgentsTacrolimus

Identifiers

PMID20169408
PMCPMC2995209
OpenAlexW1993720820

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.