ReviewJournal of biomedicine & biotechnology2010
The role of apolipoprotein E in Guillain-Barré syndrome and experimental autoimmune neuritis.
Review in Journal of biomedicine & biotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 53 citations in OpenAlex.
- Sinomenine ameliorates experimental autoimmune neuritis by suppressing pro-inflammatory immune components and restoring immune balance.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Apolipoprotein E Is Upregulated in Blood and Circulating Monocytes of Indian Patients With Visceral Leishmaniasis.Parasite immunology · 2024Article
- Article
- Analysis of Differentially Expressed Proteins Involved in Autoimmune Cirrhosis and Normal Serum by iTRAQ Proteomics.Proteomics. Clinical applications · 2019Article
- ApoE-associated modulation of neuroprotection from Aβ-mediated neurodegeneration in transgenicDisease models & mechanisms · 2019Article
- The Influence of Education and ApolipoproteinJournal of aging research · 2018Article
- Plasma disturbance of phospholipid metabolism in major depressive disorder by integration of proteomics and metabolomics.Neuropsychiatric disease and treatment · 2018Article
- Seasonal immunoregulation in a naturally-occurring vertebrate.BMC genomics · 2016Article
- Differences in the Genetic Susceptibility to Age-Related Macular Degeneration Clinical Subtypes.Investigative ophthalmology & visual science · 2015Article
- 25-hydroxyvitamin D, APOE ɛ4 genotype and cognitive function: findings from the 1958 British birth cohort.European journal of clinical nutrition · 2015Article
- Quantitative proteomics identifies host factors modulated during acute hepatitis E virus infection in the swine model.Journal of virology · 2015Article
- A Biomarker-Based Approach to Infectious Disease in the Pediatric Emergency Department.Clinical pediatric emergency medicine · 2013Article
- Depression pathogenesis and treatment: what can we learn from blood mRNA expression?BMC medicine · 2013Review
- Impairment of gastric nitrergic and NRF2 system in apolipoprotein E knockout mice.Digestive diseases and sciences · 2012Article
- Attenuated EAN in TNF-α deficient mice is associated with an altered balance of M1/M2 macrophages.PloS one · 2012Article
- Anti-inflammatory effects of tetradecylthioacetic acid (TTA) in macrophage-like cells from Atlantic salmon (Salmo salar L.).BMC immunology · 2011Article
- Cross-talk between apolipoprotein E and cytokines.Mediators of inflammation · 2011Review
- Animal models of calcific aortic valve disease.International journal of inflammation · 2011Article
- Apolipoprotein E Gene Polymorphism, Serum Lipids, and Risk of Superficial Fungal Infections in Egyptian Patients - A Preliminary Case-Controlled Study.Indian journal of dermatologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Apolipoprotein E (apoE) is a 34.2 kDa glycosylated protein characterized by its wide tissue distribution and multiple functions. ApoE has been widely studied in lipid metabolism, cardiocerebrovascular diseases, and neurodegenerative diseases like Alzheimer's disease and mild cognitive impairment, and so forth. Recently, a growing body of evidence has pointed to nonlipid related properties of apoE, including suppression of T cell proliferation, regulation of macrophage function, facilitation of lipid antigen presentation by CD1 molecules to natural killer T (NKT) cells, and modulation of inflammation and oxidation. By these properties, apoE impacts physiology and pathophysiology at multiple levels. The present paper summarizes updated studies on the immunoregulatory function of apoE, with special focus on isoform-specific effects of apoE on Guillain-Barré syndrome (GBS) and its animal model experimental autoimmune neuritis (EAN).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.