ArticleBMC public health2010
Insulin resistance and its association with the components of the metabolic syndrome among obese children and adolescents.
Article in BMC public health, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05488223 (Effect of Two Omega 3 Polyunsaturated Fatty Acid Schemes on Insulin Resistance and the Inflammatory and Lipid Profile in Obese Children), which is not on this map. Cited by 37 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Two Omega 3 Polyunsaturated Fatty Acid Schemes on Insulin Resistance and the Inflammatory and Lipid Profile in Obese Children
Who cites it
37 citing papers in PubMed.
- Dietary habits and metabolic response improve in obese children whose mothers received an intervention to promote healthy eating: randomized clinical trial.BMC public health · 2020Trial
- An after-school dance and lifestyle education program reduces risk factors for heart disease and diabetes in elementary school children.Journal of pediatric endocrinology & metabolism : JPEM · 2012Trial
- Exploring the U-shaped nonlinear relationship of CHG index with metabolic syndrome and mortality risks in metabolic syndrome patients.Lipids in health and disease · 2025Article
- The relationships among disease perception, perceived control, and self-care behaviors in hypertensive patients: Results of a cross-sectional study.Journal of education and health promotion · 2025Article
- Comparison of the Clinical Utility of Two Insulin Resistance Indices: IRI-HOMA and IRI-Belfiore in Diagnosing Insulin Resistance and Metabolic Complications in Children Based on the Results Obtained for the Polish Population.Journal of clinical medicine · 2024Article
- Assessment of Biochemical Parameters in 8- and 9-Year-Old Children with Excessive Body Weight Participating in a Year-Long Intervention Program.Journal of clinical medicine · 2023Article
- Metformin reduces insulin resistance and attenuates progressive renal injury in prepubertal obese Dahl salt-sensitive rats.American journal of physiology. Renal physiology · 2023Article
- Are glucose and insulin levels at all time points during OGTT a reliable marker of diabetes mellitus risk in pediatric obesity?Journal of endocrinological investigation · 2023Article
- Sociodemographic inequalities in cardiovascular risk factors among adolescents from indigenous areas in Chiapas, Mexico.Cadernos de saude publica · 2023Article
- [Metabolic profile and concentration of ghrelin and obestatin in children and adolescents with obesity].Revista medica del Instituto Mexicano del Seguro Social · 2022Article
- The epidemiology, clinical, biochemical, immunological and radiological features of youth onset type 2 diabetes mellitus in the state of Qatar.Diabetology international · 2022Article
- Severe Quantitative Scale of Acanthosis Nigricans in Neck is Associated with Abdominal Obesity, HOMA-IR, and Hyperlipidemia in Obese Children from Mexico City: A Cross-Sectional Study.Dermatology research and practice · 2022Article
- Impact of Insulin Resistance on Cardiometabolic Risk Factors and an Anthropometry-Based Predictive Nomogram for Insulin Resistance Among Adolescents in China.Frontiers in endocrinology · 2022Article
- Risk Assessment and Determination of Factors That Cause the Development of Hyperinsulinemia in School-Age Adolescents.Medicina (Kaunas, Lithuania) · 2021Article
- Hormone resistance in children: what primary care physicians need to know.Acta bio-medica : Atenei Parmensis · 2021Article
- Relationship between Quantitative Sonographic Measurements and Serum Biochemical Parameters in Childhood Obesity.Pediatric gastroenterology, hepatology & nutrition · 2021Article
- Prevalence of Metabolic Syndrome and Impaired Glucose Metabolism among 10- to 17-Year-Old Overweight and Obese Lithuanian Children and Adolescents.Obesity facts · 2021Article
- Comparison of different criteria for the definition of insulin resistance and its relationship to metabolic risk in children and adolescents.Annals of pediatric endocrinology & metabolism · 2020Article
- The Relationship Between Corneal Nerve Density and Hemoglobin A1c in Patients With Prediabetes and Type 2 Diabetes.Investigative ophthalmology & visual science · 2020Article
- Endocrine-Disrupting Chemicals and Insulin Resistance in Children.Biomedicines · 2020Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInsulin resistance is the primary metabolic disorder associated with obesity; yet little is known about its role as a determinant of the metabolic syndrome in obese children. The aim of this study is to assess the association between the degree of insulin resistance and the different components of the metabolic syndrome among obese children and adolescents.
methodsAn analytical, cross-sectional and population-based study was performed in forty-four public primary schools in Campeche City, Mexico. A total of 466 obese children and adolescents between 11-13 years of age were recruited. Fasting glucose and insulin concentrations, high density lipoprotein cholesterol, triglycerides, waist circumference, systolic and diastolic blood pressures were measured; insulin resistance and metabolic syndrome were also evaluated.
resultsOut of the total population studied, 69% presented low values of high density lipoprotein cholesterol, 49% suffered from abdominal obesity, 29% had hypertriglyceridemia, 8% presented high systolic and 13% high diastolic blood pressure, 4% showed impaired fasting glucose, 51% presented insulin resistance and 20% metabolic syndrome. In spite of being obese, 13% of the investigated population did not present any metabolic disorder. For each one of the components of the metabolic syndrome, when insulin resistance increased so did odds ratios as cardiometabolic risk factors.
conclusionsRegardless of age and gender an increased degree of insulin resistance is associated with a higher prevalence of disorders in each of the components of the metabolic syndrome and with a heightened risk of suffering metabolic syndrome among obese children and adolescents.
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