Other lipid agents × adverse events & safety

TrialThe New England journal of medicine2010

Effects of medical therapies on retinopathy progression in type 2 diabetes.

ACCORD Study Group et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedrandomised · 10,251 people · 2010

Randomised comparison

Lowered adverse events & safety

−33%−49% to −13%

Bigger than 7 in 10 for adverse events & safety

As reported

OR 0.67, 95% CI 0.51–0.87

Randomised comparison

Lowered adverse events & safety

−40%−58% to −13%

Bigger than 7 in 10 for adverse events & safety

As reported

OR 0.60, 95% CI 0.42–0.87

Range includes no effect

No clear effect on adverse events & safety

+23%−16% to +79%

Bigger than 5 in 10 for adverse events & safety

As reported

OR 1.23, 95% CI 0.84–1.79

Three numbers in the abstract

the abstract, start to end

standard therapy (adjusted odds ratio, 0.67; 95% confidence interval [CI], 0.51 to 0.87; P=0.003); 6.5% with fenofibrate for intensive dyslipidemia therapy, versus 10.2% with placebo (adjusted odds ratio, 0.60; 95% CI, 0.42 to 0.87; P=0.006); and 10.4% with intensive blood-pressure therapy, versus 8.8% with standard therapy (adjusted odds ratio, 1.23; 95% CI, 0.84 to 1.79; P=0.29).

← favours treatmentfavours comparator →
could be chance
Adverse events & safety
OR 0.670.51–0.87
Adverse events & safety
OR 0.600.42–0.87
Adverse events & safety
OR 1.230.84–1.79
Other lipid agentsAdverse events & safety

Other lipid agents × adverse events & safetyharms?mixed

unlikelylikely
0.000.00 without it
← favours treatmentfavours comparator →
this papermore certainless certain
1 / 5

550 papers cite itlatest 60 shown

2010
2021
2022
2023
2024
2025
2026
this paperpooled ittrialcites it

2 trials

Full record →Abstract, authors, funding and every citing paper · PMID 20587587