Evidence map›Paper›PMID 20651276›Full record

GuidelineStroke2010

Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.

Lewis B Morgenstern, J Claude Hemphill, Craig Anderson, Kyra Becker, Joseph P Broderick, E Sander Connolly, Steven M Greenberg, James N Huang, R Loch MacDonald, Steven R Messé and 4 more

5 registry-linked trialsOpen access · bronzeAbstract readPractice Guideline
In one paragraph

Guideline in Stroke, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 488 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
488citing papers in PubMed, 8 pooled it
79.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02350010 unknown statusnot on this mapstarted 2015, after this paper: background citation

The Research of Etiology and Risk Factors Related to Prognosis of Intracerebral Hemorrhage in Beijing

TypeobservationalSponsorBeijing Neurosurgical InstituteRan2015 to 2017Enrolled1,500ConditionsIntracerebral HemorrhageArmsCT Angiography
NCT02367248 phase1 / phase2unknown statusnot on this mapstarted 2015, after this paper: background citation

Safety and Effectiveness Study of Deferoxamine and Xingnaojing Injection in Intracerebral Hemorrhage

TypeinterventionalSponsorCapital Medical UniversityRan2015 to 2016Enrolled180ConditionsIntracerebral HemorrhageArmsdeferoxamine, Xingnaojing injection, Normal saline
NCT04088630 early_phase1completednot on this mapstarted 2020, after this paper: background citation

Fingolimod as a Treatment of Cerebral Edema After Intracerebral Hemorrhage

TypeinterventionalSponsorWake Forest University Health SciencesRan2020 to 2024Enrolled28ConditionsIntracerebral Hemorrhage, Cerebral Edema, Stroke Hemorrhagic, Intracerebral Hemorrhage, HypertensiveArmsFingolimod, Placebo, Open-label Fingolimod
NCT05766865 completednot on this mapstarted 2019, after this paper: background citation

Effect and Safety of Surgical Intervention for Severe Spontaneous Intracerebral Hemorrhage Patients on Long-term Oral Antiplatelet Treatment

TypeobservationalSponsorBeijing Tiantan HospitalRan2019 to 2022Enrolled450ConditionsSevere Spontaneous Intracranial Hemorrhage, Long-term Antiplatelet Treatment, Emergency Surgery, ComplicationsArmsEmergency neurosurgery, Conservative treatment
NCT05975398 recruitingnot on this mapstarted 2019, after this paper: background citation

China Research for Severe Spontaneous Intracerebral Hemorrhage(CRISIH)

Typeobservational_patient_registrySponsorBeijing Tiantan HospitalRan2019 to 2030Enrolled2,000ConditionsSevere Spontaneous Intracranial Hemorrhage, Long-term Antiplatelet Treatment, Emergency Surgery, ComplicationsArmsEmergency neurosurgery, Conservative treatment
3 · Its place in the literature

Who cites it

488 citing papers in PubMed, 8 syntheses or guidelines pooled it, 1,473 citations in OpenAlex.

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428 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Lewis B Morgenstern
J Claude Hemphill
Craig Anderson
Kyra Becker
Joseph P Broderick
E Sander Connolly
Steven M Greenberg
James N Huang
R Loch MacDonald
Steven R Messé
Pamela H Mitchell
Magdy Selim
Rafael J Tamargo
American Heart Association Stroke Council and Council on Cardiovascular Nursing
American Heart Association · US

Funding

STROKE SURVEILLANCE IN A BIETHNIC COMMUNITYR01NS038916 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI LISABETH, LYNDA D, MORGENSTERN, LEWIS B · 1999 to 2023
$20.9M
THE RELATIONSHIP OF SERUM PROTEINS TO STROKE SEVERITYP50NS044283 · NINDS · UNIVERSITY OF CINCINNATI · PI TOMSICK, THOMAS A · 2002 to 2012
$17.1M
Genetic&Environment Risk Factors for Hemorrhagic StrokeR01NS036695 · NINDS · UNIVERSITY OF CINCINNATI · PI WOO, DANIEL · 1997 to 2012
$14.1M
SF-NETT: San Francisco Neurological Emergencies Trials NetworkU10NS058931 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HEMPHILL, JESSE CLAUDE · 2007 to 2016
$2.6M
Deferoxamine therapy for intracerebral hemorrhageU01NS052510 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI XI, GUOHUA · 2007 to 2010
$1.8M
Safety and Tolerability of Deferoxamine in Acute Cerebral HemorrhageR01NS057127 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SELIM, MAGDY H · 2008 to 2010
$1.0M
NINDS NIH HHS P50 NS044283NINDS NIH HHS R01 NS036695NINDS NIH HHS R01 NS038916NINDS NIH HHS R01 NS057127NINDS NIH HHS U01 NS052510NINDS NIH HHS U10 NS058931
6 · The paper itself

Abstract

purposeThe aim of this guideline is to present current and comprehensive recommendations for the diagnosis and treatment of acute spontaneous intracerebral hemorrhage.

methodsA formal literature search of MEDLINE was performed. Data were synthesized with the use of evidence tables. Writing committee members met by teleconference to discuss data-derived recommendations. The American Heart Association Stroke Council's Levels of Evidence grading algorithm was used to grade each recommendation. Prerelease review of the draft guideline was performed by 6 expert peer reviewers and by the members of the Stroke Council Scientific Statements Oversight Committee and Stroke Council Leadership Committee. It is intended that this guideline be fully updated in 3 years' time.

resultsEvidence-based guidelines are presented for the care of patients presenting with intracerebral hemorrhage. The focus was subdivided into diagnosis, hemostasis, blood pressure management, inpatient and nursing management, preventing medical comorbidities, surgical treatment, outcome prediction, rehabilitation, prevention of recurrence, and future considerations.

conclusionsIntracerebral hemorrhage is a serious medical condition for which outcome can be impacted by early, aggressive care. The guidelines offer a framework for goal-directed treatment of the patient with intracerebral hemorrhage.

Indexed as

American Heart AssociationCerebral HemorrhageDiagnosis, DifferentialDiagnostic ImagingEvidence-Based MedicineHumansUnited States

Identifiers

PMID20651276
PMCPMC4462131
OpenAlexW2138238488

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.