SynthesisBMC musculoskeletal disorders2010
Anterior knee pain in younger adults as a precursor to subsequent patellofemoral osteoarthritis: a systematic review.
Synthesis in BMC musculoskeletal disorders, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 2 syntheses or guidelines pooled it, 194 citations in OpenAlex.
- Knee orthoses for treating patellofemoral pain syndrome.The Cochrane database of systematic reviews · 2015Pooled it
- Patellar taping for patellofemoral pain syndrome in adults.The Cochrane database of systematic reviews · 2012Pooled it
- Efficacy of a Mobile Multidisciplinary Digital Therapeutics App for Patellofemoral Pain: Randomized Controlled Trial.JMIR mHealth and uHealth · 2025Trial
- The application of a digital therapeutic reveals superior outcome compared to standard care in patients with anterior knee pain-a randomized controlled trial.Archives of orthopaedic and trauma surgery · 2025Trial
- Exercise-Induced Changes in Femoral Cartilage Thickness in Patients With Patellofemoral Pain.Journal of athletic training · 2023Trial
- Associations of foot and ankle characteristics with knee symptoms and function in individuals with patellofemoral osteoarthritis.Journal of foot and ankle research · 2020Trial
- Effects of Trigger Point Dry Needling on Neuromuscular Performance and Pain of Individuals Affected by Patellofemoral Pain: A Randomized Controlled Trial.Journal of pain research · 2020Trial
- A questionnaire to identify patellofemoral pain in the community: an exploration of measurement properties.BMC musculoskeletal disorders · 2016Trial
- The Patella Pro study - effect of a knee brace on patellofemoral pain syndrome: design of a randomized clinical trial (DRKS-ID:DRKS00003291).BMC musculoskeletal disorders · 2014Trial
- Efficacy of a 3 month training program on the jump-landing technique in jump-landing sports. Design of a cluster randomized controlled trial.BMC musculoskeletal disorders · 2010Trial
- Inflammatory, angiogenic and neurogenic serum biomarkers in patients with patellofemoral pain compared to healthy controls.Osteoarthritis and cartilage open · 2026Article
- Re-examining the association between region-specific pain recurrence and muscle force strategies in patients with patellofemoral pain via OpenSim and artificial intelligence: a prospective cohort study toward targeted rehabilitation.Journal of neuroengineering and rehabilitation · 2025Article
- Differences in quadriceps but not hamstrings strength in runners with varying durations of patellofemoral pain.Frontiers in sports and active living · 2025Article
- Investigating the validity of low-cost technologies for the assessment of jumping-based performances in people with patellofemoral pain.South African journal of sports medicine · 2025Article
- Management of persistent patellofemoral pain conditions using a tricompartmental offloading knee brace: a case series.The Journal of the Canadian Chiropractic Association · 2024Article
- Automated personalization of biomechanical knee model.International journal of computer assisted radiology and surgery · 2024Article
- Article
- Global research trends and hotspots in patellofemoral pain syndrome from 2000 to 2023: a bibliometric and visualization study.Frontiers in medicine · 2024Article
- The Evolution of Neuroimaging Technologies to Evaluate Neural Activity Related to Knee Pain and Injury Risk.Current reviews in musculoskeletal medicine · 2024Review
- Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPatellofemoral osteoarthritis (PFOA) is a common form of knee OA in middle and older age, but its relation to PF disorders and symptoms earlier in life is unclear. Our aim was to conduct a systematic review to investigate the strength of evidence for an association between anterior knee pain (AKP) in younger adults and subsequent PFOA.
methodsThe search strategy included electronic databases (Pubmed, EMBASE, AMED, CINAHL, Cochrane, PEDro, SportDiscus: inception to December 2009), reference lists of potentially eligible studies and selected reviews. Full text articles in any language, - identified via English titles and abstracts, were included if they were retrospective or prospective in design and contained quantitative data regarding structural changes indicative of PFOA, incident to original idiopathic AKP. Eligibility criteria were applied to titles, abstracts and full-texts by two independent reviewers. Data extraction included study location, design, date, sampling procedure, sample characteristics, AKP/PFOA definitions, follow-up duration and rate, and main findings. Foreign language articles were translated into English prior to examination.
resultsSeven articles satisfied eligibility (5 English, 2 German). Only one case-control study directly investigated a link between PFOA and prior AKP, providing level 3b evidence in favour of an association (OR 4.4; 95%CI 1.8, 10.6). Rough estimates of the annual risk of PFOA from the remaining six small, uncontrolled, observational studies (mean follow-up range: 5.7 to 23 years) ranged from 0% to 3.4%. This was not the primary aim of these studies, and limitations in design and methodology mean this data should be interpreted with caution.
conclusionsThere is a paucity of high-quality evidence reporting a link between AKP and PFOA. Further, well-designed cohort studies may be able to fill this evidence gap.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.