Evidence mapPaperPMID 20879883Full record

ReviewThe New England journal of medicine2010

Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease.

Giovanni Targher, Christopher P Day, Enzo Bonora

2 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in The New England journal of medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 843 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
843citing papers in PubMed, 11 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07020377 phase1 / phase2active not recruitingstarted 2024, after this paper: background citation

The Hepato-protective Effect of Dapagliflozin in Type 2 Diabetes Mellitus Patients (T2DM) With Nonalcoholic Fatty Liver Disease (NAFLD)

Ran2024Enrolled60Registered outcomes6Posted comparisons0ConditionsDiabetes Mellitus, Non Alcholic Fatty Liver DiseaseArmsDapagliflozin (DAPA), Negative control, Placebo
Open the trial in the graph
NCT03198572 phase4unknown statusnot on this mapstarted 2017, after this paper: background citation

Efficacy and Safety of Berberine in Non-alcoholic Steatohepatitis: a Multicentre, Randomised, Placebo-controlled Trial

TypeinterventionalSponsorFudan UniversityRan2017 to 2024Enrolled120ConditionsNon-alcoholic SteatohepatitisArmsLifestyle intervention, Placebo, Berberine
3 · Its place in the literature

Who cites it

843 citing papers in PubMed, 11 syntheses or guidelines pooled it.

  1. Relationship of fat in the pancreas with cardiovascular disease: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Pooled it
  2. Gut Microbiota and Liver Health: Meta-Analysis ofInternational journal of molecular sciences · 2025
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783 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Giovanni TargherSection of Endocrinology and Metabolism, Department of Medicine, University of Verona, Verona, Italy. giovanni.targher@univr.it
Christopher P Day
Enzo Bonora

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiopsyCardiovascular DiseasesCarotid ArteriesFatty LiverHumansIncidenceInsulin ResistanceLiverObesity, AbdominalRisk FactorsUltrasonography

Identifiers

PMID20879883

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.