Trial reportClinical rheumatology2011
The effects of strength and endurance training in patients with rheumatoid arthritis.
Trial report in Clinical rheumatology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Physical Exercise as an Adjuvant to Glucocorticoid Therapy: Clinical Recommendations and Evidence Review.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- Effectiveness of physical exercise on foot pain and function in adults with rheumatoid arthritis: systematic review and meta-analysis.Clinical rheumatology · 2026Pooled it
- Quality of reporting and nature of harms in clinical trials on supervised exercise in patients with rheumatoid arthritis or axial spondyloarthritis.Rheumatology international · 2024Pooled it
- A systematic review exploring the evidence reported to underpin exercise dose in clinical trials of rheumatoid arthritis.Rheumatology (Oxford, England) · 2020Pooled it
- The impact of physical activity on serum levels of inflammatory markers in rheumatoid arthritis: a systematic literature review.Rheumatology international · 2019Pooled it
- Trial
- Personalized exercise therapy during targeted drug therapy tapering in patients with rheumatoid arthritis: a pilot randomized controlled trial.BMC rheumatology · 2026Article
- Real-World Safety and Efficacy of Targeted Therapies in Rheumatoid Arthritis: A 5-Year, 5130-Case Follow-Up from FIRST Registry.Rheumatology and therapy · 2025Article
- Review
- Do Disease-Modifying Anti-rheumatic Drugs and Exercise Therapy Have a Combined Effect on Disease Activity in Patients with RA? A Scoping Review.Current rheumatology reports · 2023Article
- Inequity in exercise-based interventions for adults with rheumatoid arthritis: a systematic review.Rheumatology advances in practice · 2023Review
- Review
- Review
- Myopenia is associated with joint damage in rheumatoid arthritis: a cross-sectional study.Journal of cachexia, sarcopenia and muscle · 2019Article
- [Effect of long-term resistance exercise on masseter muscle mechanical hyperalgesia in rats].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2019Article
- Article
- Effects of aerobic exercise on hematologic indices of women with rheumatoid arthritis: A randomized clinical trial.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2016Article
- Aerobic exercise improves oxidant-antioxidant balance in patients with rheumatoid arthritis.Journal of physical therapy science · 2015Article
- Exercise as an anti-inflammatory therapy for rheumatic diseases-myokine regulation.Nature reviews. Rheumatology · 2015Review
- Acute resistance exercise induces antinociception by activation of the endocannabinoid system in rats.Anesthesia and analgesia · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with rheumatoid arthritis (RA) suffer from muscle loss, causing reduced muscle strength and endurance. The current study aimed to: (1) evaluate the effects of combined strength and endurance training (CT) on disease activity and functional ability in patients with RA and (2) investigate the benefits of a 6-month supervised CT program on muscle strength, cardio-respiratory fitness, and body composition of RA patients. Forty patients with RA, aged 41-73 years, were recruited for the current study. Twenty of these patients (19 females, one male) were randomly assigned to a 6-month supervised CT program; 20 patients (17 females, three males) served as controls. Within the CT program, strength training consisted of sets of weight bearing exercises for all major muscle groups. In addition to strength training, systematic endurance training was performed on a cycle ergometer two times per week. For RA patients involved in CT, disease activity (p = 0.06) and pain (p = 0.05) were reduced after the 6-month training period while general health (p = 0.04) and functional ability (p = 0.06) improved. Cardio-respiratory endurance was found to have improved significantly (by 10%) after 6 months of CT (p < 0.001). The overall strength of patients undertaking CT increased by an average of 14%. Lean body mass increased, and the percentage of body fat was found to decrease significantly (p < 0.05). A combination of strength and endurance training resulted in considerable improvements in RA patients' muscle strength and cardio-respiratory endurance, accompanied by positive changes in body composition and functional ability. Long-term training appears to be effective in reducing disease activity and associated pain and was found to have no deleterious effects.
Indexed as
Identifiers
20931346What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.