Evidence map›Paper›PMID 20934435›Full record

ReviewLife sciences2010

Functions of B56-containing PP2As in major developmental and cancer signaling pathways.

Jing Yang, Christopher Phiel

Abstract readReview
In one paragraph

Review in Life sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Targeting PP2A in cancer: an underrated option.Journal of experimental & clinical cancer research : CR · 2025
    Review
  3. Article
  4. Downregulation of protein phosphatase 2Aα in asthmatic airway smooth muscle.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Analysis of the Association of Two SNPs in the Promoter Regions of theAnimals : an open access journal from MDPI · 2022
    Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Prognostic Impact of PPP2R5C Gene Expression in Adult Acute Myeloid Leukemia Patients with Normal Cytogenetics.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2020
    Article
  14. Article
  15. Review
  16. Article
  17. The emerging roles of phosphatases in Hedgehog pathway.Cell communication and signaling : CCS · 2017
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jing YangThe Research Institute at Nationwide Children's Hospital, Department of Pediatrics, the Ohio State University, 700 Children's Dr., Columbus, OH, 43205, United States. Jing.Yang@nationwidechildrens.org
Christopher Phiel
Nationwide Children's Hospital · US

Funding

Regulation of Hedgehog signaling at the level of GliR01GM093217 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI YANG, JING · 2010 to 2013
$1.2M
NIA NIH HHS 1R01AG031833NIGMS NIH HHS 1R01GM093217-01A1NIGMS NIH HHS R01 GM093217
6 · The paper itself

Abstract

Members of the B'/B56/PR61 family regulatory subunits of PP2A determine the subcellular localization, substrate specificity, and catalytic activity of PP2A in a wide range of biological processes. Here, we summarize the structure and intracellular localization of B56-containing PP2As and review functions of B56-containing PP2As in several major developmental/cancer signaling pathways.

Indexed as

Signal TransductionAnimalsHumansNeoplasmsProtein Phosphatase 2Protein SubunitsSubstrate SpecificityProtein Phosphatase 2Protein Subunits

Identifiers

PMID20934435
PMCPMC2993835
OpenAlexW2132815419

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.