ReviewBMC pulmonary medicine2010
An integrative review of systematic reviews related to the management of breathlessness in respiratory illnesses.
Review in BMC pulmonary medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Mind-body interventions for cancer-related dyspnoea: a systematic review and meta-analysis of randomised controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Exercise training undertaken by people within 12 months of lung resection for non-small cell lung cancer.The Cochrane database of systematic reviews · 2019Pooled it
- An official American Thoracic Society statement: update on the mechanisms, assessment, and management of dyspnea.American journal of respiratory and critical care medicine · 2012Guideline
- The effect of resistance inspiratory muscle training in the management of breathlessness in patients with thoracic malignancies: a feasibility randomised trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2015Trial
- Trial
- Effect of exercise on postoperative recovery of patients with non-small cell lung cancer: a systematic review and meta-analysis.Discover oncology · 2024Article
- Effects and Usefulness of Inspiratory Muscle Training Load in Patients with Advanced Lung Cancer with Dyspnea.Journal of clinical medicine · 2023Article
- Palliative Care Early in the Care Continuum among Patients with Serious Respiratory Illness: An Official ATS/AAHPM/HPNA/SWHPN Policy Statement.American journal of respiratory and critical care medicine · 2022Article
- Verifying intervention fidelity procedures for a palliative home care intervention with pilot study results.Research in nursing & health · 2021Article
- Developing and Assessing the Effectiveness of a Nurse-Led Home-Based Educational Programme for Managing Breathlessness in Lung Cancer Patients. A Feasibility Study.Frontiers in oncology · 2020Article
- A Randomized Controlled Trial of a Non-pharmacological Intervention for Cancer-Related Dyspnea.Frontiers in oncology · 2020Article
- Manual Massage Therapy for Patients with COPD: A Scoping Review.Medicina (Kaunas, Lithuania) · 2019Article
- A systematic review of psychological interventions for adult and pediatric patients with vocal cord dysfunction.Frontiers in pediatrics · 2014Review
- Considerations in developing and delivering a non-pharmacological intervention for symptom management in lung cancer: the views of health care professionals.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBreathlessness is a debilitating and distressing symptom in a wide variety of diseases and still a difficult symptom to manage. An integrative review of systematic reviews of non-pharmacological and pharmacological interventions for breathlessness in non-malignant disease was undertaken to identify the current state of clinical understanding of the management of breathlessness and highlight promising interventions that merit further investigation.
methodsSystematic reviews were identified via electronic databases between July 2007 and September 2009. Reviews were included within the study if they reported research on adult participants using either a measure of breathlessness or some other measure of respiratory symptoms.
resultsIn total 219 systematic reviews were identified and 153 included within the final review, of these 59 addressed non-pharmacological interventions and 94 addressed pharmacological interventions. The reviews covered in excess of 2000 trials. The majority of systematic reviews were conducted on interventions for asthma and COPD, and mainly focussed upon a small number of pharmacological interventions such as corticosteroids and bronchodilators, including beta-agonists. In contrast, other conditions involving breathlessness have received little or no attention and studies continue to focus upon pharmacological approaches. Moreover, although there are a number of non-pharmacological studies that have shown some promise, particularly for COPD, their conclusions are limited by a lack of good quality evidence from RCTs, small sample sizes and limited replication.
conclusionsMore research should focus in the future on the management of breathlessness in respiratory diseases other than asthma and COPD. In addition, pharmacological treatments do not completely manage breathlessness and have an added burden of side effects. It is therefore important to focus more research on promising non-pharmacological interventions.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.