Evidence map›Paper›PMID 21172196›Full record

ArticleJournal of Crohn's & colitis2008

European evidence-based Consensus on the management of ulcerative colitis: Special situations.

Livia Biancone, Pierre Michetti, Simon Travis, Johanna C Escher, Gabriele Moser, Alastair Forbes, Jörg C Hoffmann, Axel Dignass, Paolo Gionchetti, Günter Jantschek and 8 more

RetractedErratum issued Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Journal of Crohn's & colitis, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. It is linked to trial NCT05938465 (A Phase 1b/2 Study to Demonstrate the Safety and Efficacy of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an Ileal Pouch-Anal Anastomosis), which is not on this map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05938465 phase1 / phase2recruitingnot on this mapstarted 2023, after this paper: background citation

A Phase 1b/2 Study to Demonstrate the Safety and Efficacy of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an Ileal Pouch-Anal Anastomosis (PROF). The "PROF" Study.

TypeinterventionalSponsorExegi Pharma, LLCRan2023 to 2027Enrolled50ConditionsIleal PouchArmsEXE-346, Placebo
3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Oral budesonide for induction of remission in ulcerative colitis.The Cochrane database of systematic reviews · 2015
    Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Efficacy and Safety of Adsorptive Granulocyte and Monocyte Apheresis in Elderly and Pregnant Patients With Ulcerative Colitis.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2019
    Article
  13. Article
  14. Article
  15. Review
  16. Ulcerative colitis.Lancet (London, England) · 2017
    Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

  • Expression of concern · 2022-01-24Civil Proceedings · Concerns/Issues about Data · Concerns/Issues about Results and/or Conclusions · Legal Reasons and/or Threats · · See also: https://doi.org/10.1093/ecco-jcc/jjab225 Journal was previously published by Elsevier until 2015.
  • Commented on by
  • Erratum issued
5 · Who and what money

Authors and funding

18 authors.

Livia Biancone
Pierre Michetti
Simon Travis
Johanna C Escher
Gabriele Moser
Alastair Forbes
Jörg C Hoffmann
Axel Dignass
Paolo Gionchetti
Günter Jantschek
Ralf Kiesslich
Sanja Kolacek
Rod Mitchell
Julian Panes
Johan Soderholm
Boris Vucelic
Eduard Stange
European Crohn's and Colitis Organisation (ECCO)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.